Department of Communicative Sciences and Disorders, New York University, USA.
Department of Psychology, New York University, USA.
J Fluency Disord. 2024 Sep;81:106062. doi: 10.1016/j.jfludis.2024.106062. Epub 2024 May 19.
Stuttering poses challenges to social, occupational, and educational aspects of life. Traditional behavioral therapies can be helpful but effects are often limited. Pharmaceutical treatments have been explored but there are no FDA-approved treatments for stuttering. Interest has grown in the potential use of classic psychedelics, including psilocybin and LSD, which have shown effectiveness in treating disorders with similar symptoms (e.g., anxiety, depression, PTSD). The potential effects of psychedelics on stuttering have not been explored. We conducted a preliminary investigation of self-identified stutterers who report their experiences taking classic psychedelics on the online messaging forum, Reddit. We qualitatively analyzed 114 publicly available posts, extracting meaningful units and assigning descriptor codes inductively. We then deductively organized responses into an established framework of psychedelics which includes behavioral, emotional, cognitive, belief-based, and social effects. These effects were subsequently grouped under organizing themes (positive, negative, neutral). Descriptive statistics revealed that the majority of users (74.0%) reported positive overall short-term effects particularly related to behavioral and emotional change (e.g., reduced stuttering and anxiety), but negative (9.6%), mixed (positive and negative; 4.8%), and neutral overall experiences (11.6%) were also reported. The results support the possibility that psychedelics may impact stuttering, but caution must be applied in their interpretation given the entirely uncontrolled research setting and potential adverse health effects of psychedelics as reported elsewhere. While these results do not encourage the use of psychedelics by stutterers, they suggest that future work could examine the impact of psychedelics on stuttering under supervised and in clinically controlled settings.
口吃给生活的社会、职业和教育方面带来挑战。传统的行为疗法可能会有帮助,但效果往往有限。已经探索了药物治疗方法,但目前没有 FDA 批准的口吃治疗方法。人们对口吃者使用经典迷幻药(包括裸盖菇素和 LSD)的潜在效果越来越感兴趣,这些药物已被证明对具有相似症状(如焦虑、抑郁、创伤后应激障碍)的疾病有效。迷幻药对口吃的潜在影响尚未得到探索。我们在在线留言板 Reddit 上对自我认定的口吃者进行了初步调查,他们报告了服用经典迷幻药的经历。我们对 114 个公开的帖子进行了定性分析,从中提取有意义的单位,并采用归纳法为其分配描述符代码。然后,我们根据迷幻剂的既定框架将回复进行演绎组织,其中包括行为、情感、认知、基于信仰和社会影响。这些影响随后被归入组织主题(正面、负面、中性)。描述性统计数据显示,大多数用户(74.0%)报告说短期总体效果积极,尤其是与行为和情绪变化有关(例如口吃和焦虑减少),但也有负面(9.6%)、混合(积极和消极;4.8%)和中性(11.6%)的体验。研究结果支持迷幻剂可能对口吃产生影响的可能性,但鉴于完全不受控制的研究环境和迷幻剂的潜在不良健康影响,在解释这些结果时必须谨慎。虽然这些结果不鼓励口吃者使用迷幻剂,但它们表明,未来的研究可以在监督和临床控制环境下,研究迷幻剂对口吃的影响。