运动对中风患者平衡功能的影响:随机对照试验的系统评价和荟萃分析
The effect of exercise on balance function in stroke patients: a systematic review and meta-analysis of randomized controlled trials.
作者信息
Zhou Yilun, Ren Hao, Hou Xiao, Dong Xiaosheng, Zhang Shiyan, Lv Yuanyuan, Li Cui, Yu Laikang
机构信息
Key Laboratory of Physical Fitness and Exercise, Ministry of Education, Beijing Sport University, Beijing, China.
Department of Strength and Conditioning Assessment and Monitoring, Beijing Sport University, Beijing, China.
出版信息
J Neurol. 2024 Aug;271(8):4751-4768. doi: 10.1007/s00415-024-12467-1. Epub 2024 Jun 4.
OBJECTIVE
A growing body of studies has examined the effect of exercise on balance function in stroke patients, with conflicting findings. This study aimed to investigate the effect of exercise on balance function in stroke patients and to determine the optimal exercise prescription for stroke patients.
METHODS
We conducted an extensive search across various databases, including PubMed, Web of Science, EBSCO, Cochrane, and Scopus. The search was conducted until March 11th, 2024. Data were pooled using the weighted mean difference (WMD) and 95% confidence interval.
RESULTS
Twenty-nine studies fulfilled the inclusion criteria. Exercise significantly improved Berg balance scale (BBS, WMD, 5.24, P < 0.00001) and timed up and go test (TUG, WMD, - 2.91, P < 0.00001) in stroke patients. Subgroup analyses showed that aerobic exercise (WMD, 6.71, P = 0.003), exercise conducted ≥ 8 weeks (WMD, 6.43, P < 0.00001), > 3 times per week (WMD, 6.18, P < 0.00001), ≥ 60 min per session (WMD, 6.40, P < 0.0001), and ≥ 180 min per week (WMD, 7.49, P < 0.00001) were more effective in improving BBS.
CONCLUSIONS
Exercise improved balance function in stroke patients, and aerobic exercise might be the most effective intervention. To improve balance function, this meta-analysis provides clinicians with evidence to recommend that stroke patients participate in a minimum of 8 weeks of exercise at least 3 times per week for more than 60 min per session, with a goal of 180 min per week being achieved by increasing the frequency of exercise.
目的
越来越多的研究探讨了运动对中风患者平衡功能的影响,但结果相互矛盾。本研究旨在调查运动对中风患者平衡功能的影响,并确定中风患者的最佳运动处方。
方法
我们在多个数据库中进行了广泛检索,包括PubMed、科学网、EBSCO、考克兰图书馆和Scopus。检索持续到2024年3月11日。使用加权平均差(WMD)和95%置信区间对数据进行合并。
结果
29项研究符合纳入标准。运动显著改善了中风患者的伯格平衡量表(BBS,WMD,5.24,P < 0.00001)和计时起立行走测试(TUG,WMD,−2.91,P < 0.00001)。亚组分析表明,有氧运动(WMD,6.71,P = 0.003)、持续≥8周的运动(WMD,6.43,P < 0.00001)、每周>3次的运动(WMD,6.18,P < 0.00001)、每次运动≥60分钟(WMD,6.40,P < 0.0001)以及每周≥180分钟(WMD,7.49,P < 0.00001)在改善BBS方面更有效。
结论
运动改善了中风患者的平衡功能,有氧运动可能是最有效的干预措施。为改善平衡功能,本荟萃分析为临床医生提供了证据,建议中风患者每周至少进行3次运动,每次运动超过60分钟,持续至少8周,并通过增加运动频率实现每周180分钟的目标。