在瑞典出生和非瑞典出生的初级保健患者中，首次发生心血管疾病的 10 年估计风险。

The estimated 10-year risk of first-onset cardiovascular disease in Swedish-born and non-Swedish-born primary healthcare patients.

机构信息

Medical programme, Karolinska Institutet, Stockholm, Sweden.

Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Alfred Nobels allé 23, Stockholm, SE-14183, Sweden.

出版信息

BMC Prim Care. 2024 Jun 4;25(1):198. doi: 10.1186/s12875-024-02446-w.

DOI:10.1186/s12875-024-02446-w

PMID:38835002

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11149177/

Abstract

BACKGROUND

SCORE2 has been introduced as an updated risk assessment tool for calculating the 10-year risk of first-onset cardiovascular disease (CVD). However, it does not account for ethnicity or socioeconomic status, known to affect CVD risk. This study investigated and compared SCORE2 estimates in Swedish-born and non-Swedish-born primary healthcare patients. The second aim was to examine if several risk factors could explain differences in CVD risk between the groups.

METHODS

This was an observational, cross-sectional study. Data were obtained from the 4D Diabetes Project study, providing a total of 444 participants aged between 40 and 69 years. All participants had complete risk variable data necessary for the SCORE2 tool and no history of previous CVD. Descriptive analysis was conducted to compare distributions of risk factors between Swedes and immigrants and odds ratios of risk factors amongst these two groups in correlation to elevated CVD risk were calculated using logistic regression.

RESULTS

Swedish-born patients showed a significantly higher risk of elevated CVD risk estimates (≥ 2.5% CVD risk increase for individuals < 50 years, respectively, ≥ 5% for individuals aged 51-69) than the non-Swedish-born population, even after adjustment for educational level (OR = 1.61, 95% CI 1.08-2.39). Weekly alcohol consumption implicated a risk of being classified as high risk of CVD risk, regardless of country of birth (OR = 1.93 CI 1.25-3.00). However, Swedes accounted for most of the alcohol consumption (62.6% vs. 19.6%). No other explanatory variable showed significance in association with elevated CVD risk.

CONCLUSIONS

Swedish-born patients were found to be at higher risk of an increased 10-year CVD risk. The association of alcohol consumption with elevated CVD risk needs to be further studied in longitudinal studies in representative populations, notably among Sweden's diverse ethnic groups.

摘要

背景

SCORE2 已被引入作为一种更新的风险评估工具，用于计算首次发生心血管疾病（CVD）的 10 年风险。然而，它没有考虑到已知会影响 CVD 风险的种族或社会经济地位。本研究调查并比较了瑞典出生和非瑞典出生的初级保健患者的 SCORE2 估计值。第二个目的是研究是否有几个风险因素可以解释两组之间 CVD 风险的差异。

方法

这是一项观察性、横断面研究。数据来自 4D 糖尿病项目研究，共纳入 444 名年龄在 40 至 69 岁之间的参与者。所有参与者均有完整的 SCORE2 工具所需的风险变量数据，且无既往 CVD 病史。进行描述性分析以比较瑞典人和移民之间的风险因素分布，并使用逻辑回归计算这两组人群中与 CVD 风险升高相关的风险因素的比值比。

结果

与非瑞典出生人群相比，瑞典出生的患者具有明显更高的 CVD 风险升高估计值（<50 岁个体的 CVD 风险增加分别≥2.5%，51-69 岁个体的 CVD 风险增加分别≥5%），即使在调整了教育水平后也是如此（OR=1.61，95%CI 1.08-2.39）。每周饮酒量无论其出生地如何，都与 CVD 风险升高相关（OR=1.93，95%CI 1.25-3.00）。然而，瑞典人占大多数饮酒量（62.6%比 19.6%）。没有其他解释变量与升高的 CVD 风险有显著关联。