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乳腺手术中的血管性血友病:病例报告

Von Willebrand's disease in breast surgery: case report.

作者信息

Rodríguez Lina, Monroy Martha, Guerrero Marco E, Villarroya Natalia

机构信息

Plastic Surgeon, Clínica Portoazul, Barranquilla-Atlántico, 080001, Colombia.

Anesthesiology and Resuscitation, Clínica Portoazul, Barranquilla-Atlántico, 080001, Colombia.

出版信息

J Surg Case Rep. 2024 Jun 4;2024(6):rjae395. doi: 10.1093/jscr/rjae395. eCollection 2024 Jun.

DOI:10.1093/jscr/rjae395
PMID:38835948
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11149459/
Abstract

Von Willebrand disease is an inherited disorder characterized by deficiency of von Willebrand factor, which contributes to platelet adhesion to the endothelium. Patients with coagulation disorders present a challenge at the time of surgery due to the high risk of presenting heavy bleeding within the procedure or postoperative hematomas. We present a case of a 56-year-old woman with Type 1 von Willebrand's disease who was scheduled for breast explantation with autologous reconstruction, due to the presence of long-standing breast implants. The case was satisfactorily managed by a multidisciplinary team formed by plastic surgery, hematology, and anesthesiology, individualizing the management for the patient's case, obtaining good results and a safe procedure.

摘要

血管性血友病是一种遗传性疾病,其特征是血管性血友病因子缺乏,该因子有助于血小板黏附于内皮。由于手术过程中出现大出血或术后血肿的风险很高,凝血障碍患者在手术时面临挑战。我们报告一例56岁1型血管性血友病女性患者,因长期存在乳房植入物而计划进行乳房假体取出并自体重建手术。该病例由整形外科、血液科和麻醉科组成的多学科团队进行了满意的处理,针对患者的具体情况进行个体化管理,取得了良好的效果并确保了手术安全。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cb9/11149459/7a54f7094d1c/rjae395f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cb9/11149459/175f3563dfb4/rjae395f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cb9/11149459/f99e4007ab6e/rjae395f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cb9/11149459/7a54f7094d1c/rjae395f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cb9/11149459/175f3563dfb4/rjae395f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cb9/11149459/f99e4007ab6e/rjae395f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3cb9/11149459/7a54f7094d1c/rjae395f3.jpg

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1
Von Willebrand's disease in breast surgery: case report.乳腺手术中的血管性血友病:病例报告
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[A rare hemostatic disorder: pseudo von Willebrand's disease].一种罕见的止血障碍:假性血管性血友病
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The rapid differentiation of type IIb von Willebrand's disease from platelet-type (pseudo-) von Willebrand's disease by the "neutral" monoclonal antibody binding assay.通过“中性”单克隆抗体结合试验快速区分IIb型血管性血友病与血小板型(假性)血管性血友病。
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Giant platelet disorder in a patient with type 2B von Willebrand's disease.2B型血管性血友病患者的巨大血小板疾病
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本文引用的文献

1
Management of complications following implant-based breast reconstruction: a narrative review.基于植入物的乳房重建术后并发症的管理:一项叙述性综述。
Ann Transl Med. 2023 Dec 20;11(12):416. doi: 10.21037/atm-23-1384. Epub 2023 Jul 12.
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Abdominoplasty in a Patient With Type 3 von Willebrand Disease: A Case Report.3 型血管性血友病患者行腹部整形术:病例报告。
Ann Plast Surg. 2024 Jan 1;92(1):133-136. doi: 10.1097/SAP.0000000000003711. Epub 2023 Oct 23.
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Prophylactic and therapeutic strategies for intraoperative bleeding in women with von Willebrand disease and heavy menstrual bleeding: A systematic review.
预防和治疗 von Willebrand 病和月经过多女性术中出血的策略:系统评价。
Blood Rev. 2023 Nov;62:101131. doi: 10.1016/j.blre.2023.101131. Epub 2023 Sep 7.
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Use of Tranexamic Acid in Liposculpture: A Double-Blind, Multicenter, Randomized Clinical Trial.脂肪抽吸术中氨甲环酸的应用:一项双盲、多中心、随机临床试验。
Plast Reconstr Surg. 2022 Sep 1;150(3):569-577. doi: 10.1097/PRS.0000000000009434. Epub 2022 Jun 28.
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Von Willebrand's Disease.血管性血友病
N Engl J Med. 2016 Nov 24;375(21):2067-2080. doi: 10.1056/NEJMra1601561.
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Reoperation for haematoma after breast reduction with preoperative administration of low-molecular-weight heparin: experience in 720 patients.术前应用低分子肝素致乳房缩小术后血肿再次手术治疗:720 例患者的经验。
J Plast Reconstr Aesthet Surg. 2012 Nov;65(11):1513-7. doi: 10.1016/j.bjps.2012.05.027. Epub 2012 Jun 23.
8
Thrombotic adverse events to coagulation factor concentrates for treatment of patients with haemophilia and von Willebrand disease: a systematic review of prospective studies.用于治疗血友病和血管性血友病患者的凝血因子浓缩物的血栓不良事件:前瞻性研究的系统评价。
Haemophilia. 2012 May;18(3):e173-87. doi: 10.1111/j.1365-2516.2012.02758.x. Epub 2012 Feb 15.
9
Perioperative management of acquired von Willebrand disease in cardiac surgery: type 2B or not 2B?心脏手术中获得性血管性血友病的围手术期管理:2B型还是非2B型?
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The laboratory approach to inherited and acquired coagulation factor deficiencies.遗传性和获得性凝血因子缺乏症的实验室检测方法。
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