Terént A, Hagfall O, Cederholm U
Acta Med Scand. 1985;217(1):47-53. doi: 10.1111/j.0954-6820.1985.tb01633.x.
The influence on glycosylated hemoglobin (HbA1) of formal education as compared with self-monitoring of blood glucose (SMBG) was studied in a randomized 18-month trial. All adult type I diabetics in a community were identified. Forty-one of these patients had had diabetes for 20 years or less. Thirty-seven patients were included in the study and finally randomized into four groups. Ten patients received individual formal education followed by SMBG, eight patients were instructed in SMBG without pre-education, nine patients were given only formal education and 10 patients made up a reference group. Education did not improve the mean HbA1 values. SMBG resulted in a decrease by 2% in HbA1, from 12 to 10% (p less than 0.05). The final HbA1 level, however, did not differ significantly between any of the groups. SMBG was accepted by 80% of the patients. The liability to hypoglycemia was about equal in the four groups. It was concluded that SMBG, but not education, improved metabolic control to a certain degree.
在一项为期18个月的随机试验中,研究了正规教育与自我血糖监测(SMBG)对糖化血红蛋白(HbA1)的影响。确定了社区内所有成年I型糖尿病患者。其中41名患者患糖尿病20年或更短时间。37名患者被纳入研究并最终随机分为四组。10名患者接受个体正规教育,随后进行自我血糖监测,8名患者在未接受预教育的情况下接受自我血糖监测指导,9名患者仅接受正规教育,10名患者组成一个参照组。教育并未改善平均HbA1值。自我血糖监测使HbA1降低了2%,从12%降至10%(p<0.05)。然而,最终各组之间的HbA1水平并无显著差异。80%的患者接受自我血糖监测。四组患者发生低血糖的倾向大致相同。得出的结论是,自我血糖监测而非教育在一定程度上改善了代谢控制。