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Myasthenic crises are associated with negative long-term outcomes in myasthenia gravis.

作者信息

Mück Anna, Pfeuffer Steffen, Mir Lara, Genau Sonja, Emde Julia, Olbricht Linus, Omar Omar A, Blaes Franz, Best Christoph, Huttner Hagen B, Krämer Heidrun H

机构信息

Department of Neurology, Justus Liebig University, Klinikstrasse 33, 35392, Giessen, Germany.

Department of Neurology, Klinikum Oberberg, Gummersbach, Germany.

出版信息

J Neurol. 2024 Aug;271(8):5650-5655. doi: 10.1007/s00415-024-12478-y. Epub 2024 Jun 5.

DOI:10.1007/s00415-024-12478-y
PMID:38839637
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11319364/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ce6/11319364/bc3c56c58e94/415_2024_12478_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ce6/11319364/bc3c56c58e94/415_2024_12478_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ce6/11319364/bc3c56c58e94/415_2024_12478_Fig1_HTML.jpg

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Myasthenic crises are associated with negative long-term outcomes in myasthenia gravis.重症肌无力危象与重症肌无力的不良长期预后相关。
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本文引用的文献

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Ravulizumab: A Review in Generalised Myasthenia Gravis.拉维珠单抗:在全身性重症肌无力中的应用评价。
Drugs. 2023 Jun;83(8):717-723. doi: 10.1007/s40265-023-01877-6. Epub 2023 May 11.
2
Myasthenic crisis.肌无力危象。
Muscle Nerve. 2023 Jul;68(1):8-19. doi: 10.1002/mus.27832. Epub 2023 Apr 28.
3
Independent risk factors for myasthenic crisis and disease exacerbation in a retrospective cohort of myasthenia gravis patients.回顾性重症肌无力患者队列中肌无力危象和疾病恶化的独立危险因素。
J Neuroinflammation. 2022 Apr 12;19(1):89. doi: 10.1186/s12974-022-02448-4.
4
Patients With Myasthenia Gravis With Acute Onset of Dyspnea: Predictors of Progression to Myasthenic Crisis and Prognosis.急性起病呼吸困难的重症肌无力患者:进展为重症肌无力危象的预测因素及预后
Front Neurol. 2021 Nov 18;12:767961. doi: 10.3389/fneur.2021.767961. eCollection 2021.
5
Safety, efficacy, and tolerability of efgartigimod in patients with generalised myasthenia gravis (ADAPT): a multicentre, randomised, placebo-controlled, phase 3 trial.依氟鸟氨酸苷单抗在全身性重症肌无力患者中的安全性、疗效和耐受性(ADAPT):一项多中心、随机、安慰剂对照、3 期临床试验。
Lancet Neurol. 2021 Jul;20(7):526-536. doi: 10.1016/S1474-4422(21)00159-9.
6
Clinical characteristics and outcomes of thymoma-associated myasthenia gravis.胸腺瘤相关重症肌无力的临床特征和结局。
Eur J Neurol. 2021 Jun;28(6):2083-2091. doi: 10.1111/ene.14820. Epub 2021 Mar 30.
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Pathomechanisms and Clinical Implications of Myasthenic Syndromes Exacerbated and Induced by Medical Treatments.药物治疗诱发和加重的肌无力综合征的发病机制及临床意义
Front Mol Neurosci. 2020 Aug 14;13:156. doi: 10.3389/fnmol.2020.00156. eCollection 2020.
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Myasthenic crisis demanding mechanical ventilation: A multicenter analysis of 250 cases.需要机械通气的肌无力危象:250 例多中心分析。
Neurology. 2020 Jan 21;94(3):e299-e313. doi: 10.1212/WNL.0000000000008688. Epub 2019 Dec 4.
9
Understanding the burden of refractory myasthenia gravis.了解难治性重症肌无力的负担。
Ther Adv Neurol Disord. 2019 Mar 1;12:1756286419832242. doi: 10.1177/1756286419832242. eCollection 2019.
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