RNA聚合酶III转录单位散布于人类非α-珠蛋白基因之间。
RNA polymerase III transcriptional units are interspersed among human non-alpha-globin genes.
作者信息
Duncan C, Biro P A, Choudary P V, Elder J T, Wang R R, Forget B G, de Riel J K, Weissman S M
出版信息
Proc Natl Acad Sci U S A. 1979 Oct;76(10):5095-9. doi: 10.1073/pnas.76.10.5095.
Abstract
Cloned human DNA fragments containing globin genes are transcribed in vitro to form discrete RNA species. One transcription unit is located approximately 1500 base pairs upstream from the G-gamma-globin gene. This transcript is partially homologous to a polymerase III template located approximately 1000 base pairs upstream from the delta-globin gene and to DNA located a short distance downstream from the beta-globin gene.
摘要
含有珠蛋白基因的克隆化人类DNA片段在体外转录形成离散的RNA种类。一个转录单位位于G-γ-珠蛋白基因上游约1500个碱基对处。该转录本与位于δ-珠蛋白基因上游约1000个碱基对处的聚合酶III模板以及位于β-珠蛋白基因下游短距离处的DNA部分同源。
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