一匹弗赖贝格母马身上发生的具有上皮嗜性的多中心性中等大小B细胞淋巴瘤。

A multicentric intermediate-size B-cell lymphoma with epitheliotropism in a Freiberger mare.

作者信息

Veiga Inês Berenguer, Affolter Verena K, Moore Peter F, Maia-Nussbaumer Päivi de Jesus, Gerber Vincenz, Unger Lucia, Dettwiler Martina

机构信息

Institute of Animal Pathology, Vetsuisse Bern, University of Bern, Bern, Switzerland.

Department of Pathology, Microbiology Immunology, School of Veterinary Medicine, University California Davis, Davis, California, USA.

出版信息

Vet Dermatol. 2024 Oct;35(5):573-577. doi: 10.1111/vde.13270. Epub 2024 Jun 7.

DOI:10.1111/vde.13270

PMID:38845482

Abstract

This report describes a multicentric intermediate-size B-cell lymphoma with epitheliotropism in a Freiberger mare affecting multiple mucous membranes, skin and internal organs. The clonal neoplastic B-cell population was accompanied by numerous reactive polyclonal small T cells. Differential diagnoses for these unusual findings are discussed.

摘要

本报告描述了一匹弗赖贝格尔母马发生的多中心性中等大小B细胞淋巴瘤，该淋巴瘤具有亲上皮性，累及多个黏膜、皮肤和内脏器官。克隆性肿瘤性B细胞群体伴有大量反应性多克隆小T细胞。文中讨论了这些异常发现的鉴别诊断。