Arora Suryansh, Mehra Shibani, Bhattacharya Ipshita, Nanda Civilee
Department of Radiodiagnosis, ABVIMS and Dr. RML Hospital, New Delhi, Delhi, India.
Department of Dermatology, Venereology and Leprosy, ESI-PGIMSR, New Delhi, Delhi, India.
Indian Dermatol Online J. 2024 Apr 29;15(3):480-486. doi: 10.4103/idoj.idoj_500_23. eCollection 2024 May-Jun.
International Society for the Study of Vascular Anomalies classification defines Congenital Limb Overgrowth Vascular Syndromes (CLOS) as a subset of vascular syndromes with other abnormalities that present with unilateral limb overgrowth. It includes Klippel-Trenaunay Syndrome, Parkes-Weber Syndrome, CLOVES (Congenital Lipomatous Overgrowth, Vascular Malformations, Epidermal Nevi, Spinal/Skeletal Anomalies/Scoliosis) Syndrome, Proteus Syndrome, PTEN Hamartomatous Syndrome, and Fibroadipose Vascular Anomaly. Due to their rare and complex nature, a multidisciplinary approach to diagnosis and treatment is required. A thorough clinical and radiological workup can go miles in reflecting on the patient's outcome. Here we report five cases of CLOS with their detailed dermato-radiological profiles.
国际血管异常研究学会分类将先天性肢体过度生长血管综合征(CLOS)定义为伴有单侧肢体过度生长及其他异常的血管综合征的一个子集。它包括克-特综合征、帕克斯-韦伯综合征、CLOVES(先天性脂肪瘤过度生长、血管畸形、表皮痣、脊柱/骨骼异常/脊柱侧弯)综合征、变形综合征、PTEN错构瘤综合征以及纤维脂肪性血管异常。由于其罕见性和复杂性,需要采用多学科方法进行诊断和治疗。全面的临床和放射学检查对于评估患者的预后大有帮助。在此,我们报告5例CLOS病例及其详细的皮肤放射学特征。