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鼻腔软骨母细胞型骨肉瘤:一种罕见且易误诊的表现。

Chondroblastic osteosarcoma of the nasal cavity: an exceptional and misdiagnosed presentation.

作者信息

Aaboudech Taha Yassine, El Ouazzani Hafsa, Kadiri Habiba, Benabdenbi Hanae, Rguieg Naji, El Ouali Ibtissam, El Kettani N Ech-Cherif, Zouaidia Fouad, Cherradi Nadia

机构信息

Pathology Department, Rabat Specialty Hospital, Rabat 10100, Morocco.

Mohammed V University in Rabat, Rabat 10000, Morocco.

出版信息

J Surg Case Rep. 2024 Jun 6;2024(6):rjae409. doi: 10.1093/jscr/rjae409. eCollection 2024 Jun.

Abstract

Chondroblastic osteosarcoma of the nasal cavity is a rare and aggressive tumor that presents diagnostic challenges due to its variable clinical and radiological features. Histological analysis is crucial for an accurate diagnosis, despite morphological similarities with chondrosarcoma. We present a case of primary craniofacial chondroblastic osteosarcoma originating from the nasal cavity in a 17-year-old adolescent. The tumor was characterized by cartilaginous lobules and spindle cell proliferation with osteoid matrix deposition. Immunohistochemical analysis supported the diagnosis. This case highlights the rarity of this particular presentation and emphasizes the significance of accurate diagnosis through histopathological evaluation to achieve optimal management.

摘要

鼻腔软骨母细胞型骨肉瘤是一种罕见且侵袭性强的肿瘤,因其临床和放射学特征多变而带来诊断挑战。尽管与软骨肉瘤在形态上有相似之处,但组织学分析对于准确诊断至关重要。我们报告一例17岁青少年原发于鼻腔的颅面部软骨母细胞型骨肉瘤病例。该肿瘤的特征为软骨小叶和梭形细胞增生,并伴有类骨质基质沉积。免疫组化分析支持该诊断。此病例凸显了这种特殊表现的罕见性,并强调了通过组织病理学评估进行准确诊断以实现最佳治疗的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8d3/11155414/12a1954ed776/rjae409f1.jpg

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