De Rosa Rosanna Carmela, Falso Fabrizio, Viola Gianfranco, Barberio Massimiliano, Giurazza Roberto
Department of Anesthesia and Intensive Care, AORN Ospedali dei Colli - "D. Cotugno" Hospital, Naples, ITA.
Cureus. 2024 May 7;16(5):e59841. doi: 10.7759/cureus.59841. eCollection 2024 May.
is a Gram-negative bacterium, commonly found as a commensal germ in the oral cavity of dogs and cats. It is an opportunistic pathogen, but, in specific situations, it can cause very severe diseases, including arthritis, pleuritis, endocarditis, sepsis, and, in extremely rare cases, meningoencephalitis. The predisposing situations include immunosuppression, liver cirrhosis, splenectomy, hemochromatosis, beta thalassemia major (Cooley's anemia), and alcohol abuse. In this report, we describe the case of a 48-year-old male patient, with a medical history of several predisposing conditions, who developed a severe case of meningoencephalitis caused by , following a dog bite on his hand. The patient was successfully treated for his meningitis, but subsequently he developed a hospital-acquired septic shock from , which was treated with targeted antibiotic therapy and sequential extracorporeal blood purification therapies using Oxiris™ and Toraymyxin™ hemofilters.
是一种革兰氏阴性菌，常见于犬猫口腔中作为共生菌。它是一种机会致病菌，但在特定情况下，可引发非常严重的疾病，包括关节炎、胸膜炎、心内膜炎、败血症，在极其罕见的情况下还可引发脑膜脑炎。诱发情况包括免疫抑制、肝硬化、脾切除术、血色素沉着症、重型β地中海贫血（库利贫血）和酗酒。在本报告中，我们描述了一名48岁男性患者的病例，该患者有多种诱发疾病的病史，在手部被狗咬伤后，因感染引发了严重的脑膜脑炎。该患者的脑膜炎得到了成功治疗，但随后因感染出现了医院获得性感染性休克，采用靶向抗生素治疗以及使用Oxiris™和Toraymyxin™血液滤过器的序贯体外血液净化疗法进行治疗。
