早产儿母乳喂养母亲产后早期吸奶行为、吸奶量与泌乳启动的关系。
Early postpartum pumping behaviors, pumped milk volume, and achievement of secretory activation in breast pump-dependent mothers of preterm infants.
机构信息
Department of Pediatrics, Division of Neonatology, Seattle Children's Hospital, Seattle, WA, USA.
Department of Pediatrics, Rush University Medical Center, Chicago, IL, USA.
出版信息
J Perinatol. 2024 Nov;44(11):1597-1606. doi: 10.1038/s41372-024-02021-2. Epub 2024 Jun 8.
OBJECTIVE
Pumping studies in mothers of preterm infants are limited by self-reported pumping behaviors and non-objective measures of pumped milk volume and secretory activation (SA).
METHODS
Non-randomized observational study of first 14 days postpartum in 29 mothers of preterm infants. Smart pumps measured and stored pumping behaviors and pumped milk volume. Selective ion electrodes measured sodium and sodium:potassium ratio to determine SA. Generalized estimating equations, cluster analyses and multivariate regression were used.
RESULTS
SA was delayed (median 5.8 days) and impermanent. Each additional daily pumping increased odds of SA within 2 days by 48% (p = 0.01). High-intensity pumping mothers (N = 17) had greater daily and cumulative pumped milk volume than low-intensity pumping mothers (N = 12). Pumping variables showed daily changes in the first week, then plateaued.
CONCLUSION
The first week postpartum is critical for optimizing pumping behaviors. Accurate, objective measures of pumping behaviors, pumped milk volume and SA are a research priority.
目的
由于采用自我报告的吸奶行为以及非客观的吸奶量和分泌激活（SA）测量方法，对早产儿母亲的吸奶研究受到限制。
方法
对 29 名早产儿母亲产后第 14 天内的情况进行非随机的观察性研究。智能吸奶器测量并存储吸奶行为和吸奶量。选择性离子电极测量钠和钠钾比以确定 SA。使用广义估计方程、聚类分析和多元回归进行分析。
结果
SA 出现延迟（中位数为 5.8 天）且不持久。每天增加一次吸奶，在 2 天内 SA 的可能性增加 48%（p=0.01）。高强度吸奶的母亲（N=17）的每日和累计吸奶量高于低强度吸奶的母亲（N=12）。吸奶变量在第一周内每天都有变化，然后趋于稳定。
结论
产后第一周是优化吸奶行为的关键时期。准确、客观的吸奶行为、吸奶量和 SA 测量方法是研究的重点。
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