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美国急诊科治疗背痛的羟考酮及含羟考酮镇痛剂的使用趋势(2007 - 2018年)

Trends in oxycodone and oxycodone-containing analgesics administration for back pain in emergency departments in the USA (2007-2018).

作者信息

Chabon Jonathan, Garrido Jemer, Schreiber-Gregory Deanna, Drapkin Jefferson, Motov Sergey

机构信息

Department of Emergency Medicine, Maimonides Medical Center, Brooklyn 11219, USA.

出版信息

World J Emerg Med. 2024;15(3):169-174. doi: 10.5847/wjem.j.1920-8642.2024.002.

DOI:10.5847/wjem.j.1920-8642.2024.002
PMID:38855375
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11153367/
Abstract

BACKGROUND

To describe trends in oxycodone and oxycodone-containing analgesic prescribing for the treatment of back pain among adults in emergency departments (EDs) in the USA from 2007 to 2018.

METHODS

Data were gathered from the National Hospital Ambulatory Medical Care Survey (NHAMCS) from 2007 to 2018. The study population included individuals of all ages presenting to USA EDs. The NHAMCS reasons for visit and oxycodone drug ID codes were used to isolate patients with back pain. The main outcome was the proportion of oxycodone and oxycodone-containing analgesics prescribed for back pain in the EDs over the specified time period.

RESULTS

There was a relative decrease in the overall administration of oxycodone for back pain in the EDs by 62.3% from 2007 (244,000 visits) to 2018 (92,000 visits). The proportion of ED patients prescribed with oxycodone-containing analgesics for back pain increased among patients aged 45 years and older (from 43.8% to 57.6%), female patients (from 54.5% to 62.0%), black patients (from 22.5% to 30.4%), and Hispanic/Latino patients (from 9.4% to 19.6%). Oxycodone/acetaminophen was most prescribed and accounted for 90.2% of all oxycodone-containing analgesics in 2007, with a decrease to 68.5% in 2018. Pure oxycodone was the second most prescribed medication, accounting for 6.1% in 2007 and 31.5% in 2018.

CONCLUSION

The overall number of oxycodone-containing analgesics decreased significantly from 2007 to 2018. However, that number trended upward in 45-year-old and older, female, black, or Hispanic/Latino patients from 2007 to 2018. The total amount of pure oxycodone increased significantly from 2007 to 2008.

摘要

背景

描述2007年至2018年美国急诊科(ED)中用于治疗成人背痛的羟考酮及含羟考酮镇痛药物的处方趋势。

方法

收集2007年至2018年美国国家医院门诊医疗调查(NHAMCS)的数据。研究人群包括前往美国急诊科的所有年龄段的个体。使用NHAMCS的就诊原因和羟考酮药物识别码来筛选出背痛患者。主要结果是在特定时间段内急诊科为背痛患者开具的羟考酮及含羟考酮镇痛药物的比例。

结果

从2007年(24.4万次就诊)到2018年(9.2万次就诊),急诊科用于背痛的羟考酮总体使用量相对下降了62.3%。45岁及以上患者(从43.8%增至57.6%)、女性患者(从54.5%增至62.0%)、黑人患者(从22.5%增至30.4%)以及西班牙裔/拉丁裔患者(从9.4%增至19.6%)中,因背痛开具含羟考酮镇痛药物的急诊患者比例有所增加。2007年,羟考酮/对乙酰氨基酚的处方量最大,占所有含羟考酮镇痛药物的90.2%,到2018年降至68.5%。纯羟考酮是处方量第二大的药物,2007年占6.1%,2018年占31.5%。

结论

2007年至2018年,含羟考酮镇痛药物的总体数量显著下降。然而,2007年至2018年,45岁及以上、女性、黑人或西班牙裔/拉丁裔患者的该类药物数量呈上升趋势。2007年至2008年,纯羟考酮的总量显著增加。