Durkee Heather, Ruggeri Marco, Rohman Leana, Williams Siobhan, Ho Arthur, Parel Jean-Marie, Manns Fabrice
Ophthalmic Biophysics Center, Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 1638 NW 10 Ave, Miami, Florida 33136, USA.
Department of Biomedical Engineering, University of Miami College of Engineering, 1251 Memorial Drive, Coral Gables, Florida 33146, USA.
Biomed Opt Express. 2024 Apr 5;15(5):2876-2889. doi: 10.1364/BOE.512193. eCollection 2024 May 1.
Accommodation is the process by which the eye changes focus. These changes are the result of changes to the shape of the crystalline lens. Few prior studies have quantified the relation between lens shape and ocular accommodation, primarily at discrete static accommodation states. We present an instrument that enables measurements of the relation between changes in lens shape and changes in optical power continuously during accommodation. The system combines an autorefractor to measure ocular power, a visual fixation target to stimulate accommodation, and an optical coherence tomography (OCT) system to image the anterior segment and measure ocular distances. Measurements of ocular dimensions and refraction acquired dynamically on three human subjects are presented. The individual accommodative responses are analyzed to correlate the ocular power changes with changes in ocular dimensions.
调节是眼睛改变焦点的过程。这些变化是晶状体形状改变的结果。很少有先前的研究对晶状体形状与眼调节之间的关系进行量化，主要是在离散的静态调节状态下。我们提出了一种仪器，能够在调节过程中连续测量晶状体形状变化与屈光力变化之间的关系。该系统结合了一个自动验光仪来测量眼屈光力、一个视觉注视目标来刺激调节，以及一个光学相干断层扫描（OCT）系统来成像眼前节并测量眼内距离。展示了在三名人类受试者身上动态获取的眼尺寸和屈光测量结果。对个体的调节反应进行分析，以将眼屈光力变化与眼尺寸变化相关联。
