Chang Yu-Cherng, Mesquita Gabrielle Monterano, Williams Siobhan, Gregori Giovanni, Cabot Florence, Ho Arthur, Ruggeri Marco, Yoo Sonia H, Parel Jean-Marie, Manns Fabrice
Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, FL, USA.
Biomed Opt Express. 2019 Jan 4;10(2):411-422. doi: 10.1364/BOE.10.000411. eCollection 2019 Feb 1.
The lens equivalent refractive index (RI) is commonly used in calculations of crystalline lens power. However, accurate determination of the equivalent RI is challenging due to the need of multiple measurements with different ocular biometry devices. A custom extended-depth Spectral Domain-OCT system was utilized to provide measurements of corneal and lens surface curvatures and all intraocular distances required for determination of the lens equivalent RI. Ocular biometry and refraction were input into a computational model eye from which the equivalent RI was calculated. Results derived from human subjects of a wide age range show a decrease in RI with age and demonstrate the capability of measurements of the equivalent RI with extended-depth OCT.
晶状体等效折射率（RI）常用于计算晶状体屈光力。然而，由于需要使用不同的眼科生物测量设备进行多次测量，准确测定等效RI具有挑战性。利用定制的扩展深度光谱域光学相干断层扫描（OCT）系统来测量角膜和晶状体表面曲率以及确定晶状体等效RI所需的所有眼内距离。将眼科生物测量和验光数据输入到一个计算模型眼，从中计算等效RI。来自广泛年龄范围的人类受试者的结果显示，RI随年龄增长而降低，并证明了使用扩展深度OCT测量等效RI的能力。
