标题：库斯坦弗氏阿魏中新的苯丙素类和二硫化物二聚体 **解析**：这段文本是对库斯坦弗氏阿魏中新苯丙素类和二硫化物二聚体的描述，因此将“Ferula Kuhistanica”翻译为“库斯坦弗氏阿魏”。
New Phenylpropanoids and Disulphides Dimers from Ferula Kuhistanica.
机构信息
State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi, 830011, China.
University of the Chinese Academy of Sciences, Beijing, 100039, China.
出版信息
Chem Biodivers. 2024 Aug;21(8):e202401015. doi: 10.1002/cbdv.202401015. Epub 2024 Jul 26.
Five undescribed compounds, including three phenylpropanoid derivatives, 4'-methoxycinnamyl isobutyrate (1), 4'-methoxycinnamyl-2"-methyl butyrate (2) and (2Z)-3',4'-dimethoxycinnamyl isovalerate (3) and two disulphides dimers, kuhistanicasulphide A (7) and kuhistanicasulphide B (8) together with five known ones, including three phenylpropanoids (4-6) and two disulphides (9-10), were isolated from the roots of Ferula kuhistanica Korovin. Their structures were elucidated on the basis of spectroscopic analysis, including IR, UV, HRESIMS, NMR and quantum C NMR DP4+ probability. Anti-inflammatory and cytotoxic (Hela, A549 and HT-29 cell lines) activities of the obtained compounds was tested, which compounds 4 and 5 demonstrated good anti-inflammatory with IC values of 25.41±2.30 μM and 31.70±3.82 μM, respectively.
从新疆阿魏（Ferula kuhistanica Korovin）根部分离得到 5 个未知化合物，包括 3 个苯丙素衍生物 4'-甲氧基肉桂酰异丁酸酯（1）、4'-甲氧基肉桂酰-2"-甲基丁酸酯（2）和（2Z）-3',4'-二甲氧基肉桂酰异戊酸酯（3），2 个二硫化物二聚体，库斯坦斯卡二硫化物 A（7）和库斯坦斯卡二硫化物 B（8），以及 5 个已知化合物，包括 3 个苯丙素（4-6）和 2 个二硫化物（9-10）。基于光谱分析，包括 IR、UV、HRESIMS、NMR 和量子 C NMR DP4+概率，阐明了它们的结构。对获得的化合物进行了抗炎和细胞毒性（Hela、A549 和 HT-29 细胞系）活性测试，化合物 4 和 5 表现出良好的抗炎活性，IC 值分别为 25.41±2.30 μM 和 31.70±3.82 μM。
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