Larsson S A
Br J Haematol. 1985 Apr;59(4):593-602. doi: 10.1111/j.1365-2141.1985.tb07353.x.
Life expectancy of Swedish haemophiliacs has been estimated for the period 1831-1980. The data were derived from 948 haemophiliacs of whom 580 survived throughout 1980. Applying standard demographic techniques, median life expectancy of patients with severe haemophilia was found to have increased fivefold, from a mere 11 years during the period 1831-1920 to 56.8 years during 1961-80. The corresponding estimates for patients with moderate haemophilia were 27.5 and 71.5 years, respectively. The limited data on patients with mild haemophilia did not indicate any significant improvements in mortality. From the beginning of this century to 1980 median life expectancy for Swedish males increased from 61.7 years to 75.6 years, an increase of 23%. Analysing the last 12 years of the study (1969-80), death rates for patients with severe haemophilia below the age of 45 were not much different from those of Swedish males in the population as a whole. The investigation implies that the mortality of haemophiliacs in Sweden is approaching that of the total male population.
瑞典血友病患者1831年至1980年期间的预期寿命已得到估算。数据来源于948名血友病患者，其中580人存活至1980年。运用标准人口统计学技术，发现重度血友病患者的中位预期寿命增长了五倍，从1831年至1920年期间的仅仅11岁增至1961年至1980年期间的56.8岁。中度血友病患者的相应估算值分别为27.5岁和71.5岁。轻度血友病患者的有限数据未显示死亡率有任何显著改善。从本世纪初到1980年，瑞典男性的中位预期寿命从61.7岁增至75.6岁，增长了23%。分析该研究的最后12年（1969年至1980年），45岁以下重度血友病患者的死亡率与瑞典男性总体人群的死亡率并无太大差异。该调查表明，瑞典血友病患者的死亡率正在接近男性总人口的死亡率。
