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巴勒斯坦2型糖尿病患者贫血患病率及其与体重指数和肾功能的相关性

Prevalence of Anemia in Type 2 Diabetic Patients and ‎correlation with Body Mass Index and Kidney ‎function in Palestine.

作者信息

Fathi Alaa Elsayed, Shahwan Moyad, Hassan Nageeb, Jairoun Ammar Abdulrahman, Shahwan Monzer

机构信息

Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman, Ajman, 346, United Arab Emirates.

Centre of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, Ajman, 346, United Arab Emirates.

出版信息

Diabetes Metab Syndr Obes. 2024 Jun 6;17:2293-2301. doi: 10.2147/DMSO.S454916. eCollection 2024.

Abstract

BACKGROUND

The objective of this study was to determine the prevalence of anemia in patients with type 2 diabetes mellitus and ‎to identify the set of anthropometric and biochemical factors that jointly influence ‎the diabetic and anemic patients including ‎body mass index and kidney function.‎‎.

METHODS

A retrospective cross-sectional design study that was carried out in a private medical center ‎in Palestine. The study included a total of 453 patients with type 2 diabetes. Inclusion criteria ‎included all patients (18 years or older) suffering from type 2 Diabetes mellitus attended the ‎diabetic clinic from the 1st of January 2018, till 30th of December 2018.‎.

RESULTS

A total number of 453 diabetic patients were recruited in the study. Male constituted 48.5% ‎‎(n=220) of the study sample and 51.4% (n=233) were female. Of total 453 diabetic patients, ‎‎38.4% (95% CI, 34%-43%) had anemia. The results of statistical modeling showed that female ‎gender (AOR 18.5; 95% CI 9.35-21.97), presence of hypertension (AOR 2.11; 95% CI 1.98- ‎‎4.25), high BMI (AOR 1.101; 95% CI 1.045-1.159), high Serum Creatinine (AOR 1.72; 95% ‎CI 1.22-2.13), high BUN level (AOR 1.22; 95% CI 1.145-1.301) and low e-GFR (AOR ‎‎0.571; 95% CI 0.271-0.872) are strong determents of anemia in type 2 diabetic patients.‎.

CONCLUSION

The results of the current study revealed a high prevalence of Anemia among type 2 diabetes ‎Mellitus patients. A significant association was reported between Anemia, kidney functions and ‎body mass index.‎.

摘要

背景

本研究的目的是确定2型糖尿病患者贫血的患病率,并确定共同影响糖尿病和贫血患者的一系列人体测量和生化因素,包括体重指数和肾功能。

方法

在巴勒斯坦的一家私立医疗中心进行了一项回顾性横断面设计研究。该研究共纳入453例2型糖尿病患者。纳入标准包括2018年1月1日至2018年12月31日期间到糖尿病门诊就诊的所有(18岁及以上)2型糖尿病患者。

结果

本研究共招募了453例糖尿病患者。男性占研究样本的48.5%(n=220),女性占51.4%(n=233)。在453例糖尿病患者中,38.4%(95%CI,34%-43%)患有贫血。统计建模结果显示,女性(调整后比值比[AOR]18.5;95%CI 9.35-21.97)、高血压(AOR 2.11;95%CI 1.98-4.

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Pathophysiology of diabetes: An overview.糖尿病的病理生理学:概述
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