Nephrologist, Ethiopian Police Hospital, Addis Ababa, Ethiopia.
Department of Epidemiology, Institute of Health, Jimma University, Jimma, Ethiopia.
Ethiop J Health Sci. 2022 Mar;32(2):307-312. doi: 10.4314/ejhs.v32i2.11.
Diabetes mellitus remains the leading cause of end-stage renal disease in most countries in the world. In Ethiopia, renal complications of diabetes may remain unrecognized due to limited diagnostic resources. As a result, the prevalence of chronic kidney disease among adult diabetics in Ethiopia has not been well described. Hence, this study was aimed at assessing the prevalence of chronic kidney disease and associated factors among diabetic patients who attended the federal police hospital diabetic clinic in Addis Ababa.
A cross-sectional study was conducted among 362 Diabetes Mellitus. Data were collected using face-to-face interviewing questionnaires and analyzed using SPSS version 21.0. Binary logistic regression analyses were performed to identify predictors.
The prevalence of chronic kidney disease diagnosed by Cockcroft-Gault equation and Modification of Diet in Renal Disease equation was 14.6% and 7.7% respectively. This finding shows the prevalence of chronic kidney disease among Diabetic patients was low. Age 50-59 years [(AOR= 4.0; 95% CI:(1.2, 13)] by Cockroft-Gault equation (CG), age 60-69 years [(AOR=5.8 95% CI:(1.5,21.0)] by Modification of Diet in Renal Disease (MDRD) and (AOR;22.9 95%CI:7.1,74.2) by CG, age 70 years and above (AOR=4.7; 95 CI: 1.1, 19.7) by MDRD and (AOR= 22.9; 95%CI:7.1,74.2) by CG, BMI (AOR=0.2; 95% CI:0.1,0.4) by CG, and previous kidney disease (AOR=6.2 95%CI:2.0,8.4) by MDRD and (AOR;4.6 95%CI:1.9,10.8) C-G equation have a significant association with chronic kidney disease after an adjustment done.
The prevalence of chronic kidney disease among Diabetic patients in this study was lower. Age, BMI, and previous recurrent kidney disease were associated with chronic kidney disease. Preventive measures like giving health education and screening of patients with risk factors should get more attention.
在世界上大多数国家，糖尿病仍然是终末期肾病的主要原因。在埃塞俄比亚，由于诊断资源有限，糖尿病的肾脏并发症可能仍未被发现。因此，尚未很好地描述埃塞俄比亚成年糖尿病患者中慢性肾脏病的患病率。因此，本研究旨在评估在亚的斯亚贝巴联邦警察医院糖尿病诊所就诊的糖尿病患者中慢性肾脏病的患病率及其相关因素。
对 362 例糖尿病患者进行横断面研究。使用面对面访谈问卷收集数据，并使用 SPSS 版本 21.0 进行分析。采用二元逻辑回归分析来确定预测因素。
根据 Cockcroft-Gault 方程和改良肾脏病饮食研究（MDRD）方程诊断的慢性肾脏病患病率分别为 14.6%和 7.7%。这一发现表明，糖尿病患者中慢性肾脏病的患病率较低。年龄 50-59 岁[Cockcroft-Gault 方程（CG）的优势比（AOR）=4.0；95%置信区间（CI）：（1.2，13）]，年龄 60-69 岁[MDRD 的 AOR=5.8；95%CI：（1.5，21.0）]，年龄 70 岁及以上[MDRD 的 AOR=4.7；95%CI：（1.1，19.7）]，年龄 70 岁及以上[CG 的 AOR=22.9；95%CI：（7.1，74.2）]，BMI（CG 的 AOR=0.2；95%CI：0.1，0.4）和既往肾脏疾病（MDRD 的 AOR=6.2；95%CI：2.0，8.4）以及（CG 的 AOR=4.6；95%CI：1.9，10.8）与慢性肾脏病有显著关联。
本研究中糖尿病患者慢性肾脏病的患病率较低。年龄、BMI 和既往复发性肾病与慢性肾脏病有关。应更加重视预防措施，如对有危险因素的患者进行健康教育和筛查。
