Liang Wenqing, Zhou Chao, Zhang Hongwei, Bai Juqin, Long Hengguo, Jiang Bo, Liu Lu, Xia Linying, Jiang Chanyi, Zhang Hengjian, Zhao Jiayi
Department of Orthopaedics, Zhoushan Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University, Zhoushan, China.
Department of Orthopedics, Zhoushan Guanghua Hospital, Zhoushan, Zhejiang, China.
Front Bioeng Biotechnol. 2024 May 27;12:1389071. doi: 10.3389/fbioe.2024.1389071. eCollection 2024.
A developing use of nanotechnology in medicine involves using nanoparticles to administer drugs, genes, biologicals, or other materials to targeted cell types, such as cancer cells. In healthcare, nanotechnology has brought about revolutionary changes in the treatment of various medical and surgical conditions, including in orthopedic. Its clinical applications in surgery range from developing surgical instruments and suture materials to enhancing imaging techniques, targeted drug delivery, visualization methods, and wound healing procedures. Notably, nanotechnology plays a significant role in preventing, diagnosing, and treating orthopedic disorders, which is crucial for patients' functional rehabilitation. The integration of nanotechnology improves standards of patient care, fuels research endeavors, facilitates clinical trials, and eventually improves the patient's quality of life. Looking ahead, nanotechnology holds promise for achieving sustained success in numerous surgical disciplines, including orthopedic surgery, in the years to come. This review aims to focus on the application of nanotechnology in orthopedic surgery, highlighting the recent development and future perspective to bridge the bridge for clinical translation.
纳米技术在医学领域的一个新应用方向是利用纳米颗粒将药物、基因、生物制剂或其他物质输送到特定的细胞类型，如癌细胞。在医疗保健领域，纳米技术给包括骨科在内的各种医疗和外科疾病的治疗带来了革命性变化。其在外科手术中的临床应用涵盖从开发手术器械和缝合材料到改进成像技术、靶向给药、可视化方法以及伤口愈合程序等多个方面。值得注意的是，纳米技术在预防、诊断和治疗骨科疾病方面发挥着重要作用，这对患者的功能康复至关重要。纳米技术的融入提高了患者护理标准，推动了研究工作，促进了临床试验，并最终改善了患者的生活质量。展望未来，纳米技术有望在包括骨科手术在内的众多外科领域在未来几年取得持续成功。本综述旨在聚焦纳米技术在骨科手术中的应用，突出其最新进展和未来前景，为临床转化搭建桥梁。
