Smith G S, Lumsden J H, Wilcock B P
Can J Comp Med. 1985 Jan;49(1):43-9.
The standardization of pig neutrophil chemotaxis under agarose is described. The mean chemotactic index for pig neutrophils from six pigs measured over four days was 1.29. Comparative studies of human and pig neutrophil chemotaxis under agarose revealed a lower chemotactic index for pig neutrophils (mean of 1.18) compared to human neutrophils (mean of 2.43). The results suggest that this is due to differences intrinsic to human and pig neutrophils. In vitro pig neutrophil chemotaxis was measured in normal pigs and in pigs following experimental Salmonella typhimurium infection. Significant alterations in chemotaxis were not evident one and seven days postinfection.
本文描述了琼脂糖下猪中性粒细胞趋化性的标准化方法。对六头猪的中性粒细胞在四天内进行测量,其平均趋化指数为1.29。琼脂糖下人类和猪中性粒细胞趋化性的比较研究表明,与人类中性粒细胞(平均为2.43)相比,猪中性粒细胞的趋化指数较低(平均为1.18)。结果表明,这是由于人类和猪中性粒细胞内在的差异所致。在正常猪和实验性鼠伤寒沙门氏菌感染后的猪中测量了体外猪中性粒细胞趋化性。感染后一天和七天,趋化性没有明显的显著变化。