及时自适应干预稳定日本工人睡眠时间:微随机试验。
Just-in-Time Adaptive Intervention for Stabilizing Sleep Hours of Japanese Workers: Microrandomized Trial.
机构信息
Graduate School of Education, The University of Tokyo, Tokyo, Japan.
Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
出版信息
J Med Internet Res. 2024 Jun 11;26:e49669. doi: 10.2196/49669.
BACKGROUND
Sleep disturbance is a major contributor to future health and occupational issues. Mobile health can provide interventions that address adverse health behaviors for individuals in a vulnerable health state in real-world settings (just-in-time adaptive intervention).
OBJECTIVE
This study aims to identify a subpopulation with vulnerable sleep state in daily life (study 1) and, immediately afterward, to test whether providing mobile health intervention improved habitual sleep behaviors and psychological wellness in real-world settings by conducting a microrandomized trial (study 2).
METHODS
Japanese workers (n=182) were instructed to collect data on their habitual sleep behaviors and momentary symptoms (including depressive mood, anxiety, and subjective sleep quality) using digital devices in a real-world setting. In study 1, we calculated intraindividual mean and variability of sleep hours, midpoint of sleep, and sleep efficiency to characterize their habitual sleep behaviors. In study 2, we designed and conducted a sleep just-in-time adaptive intervention, which delivered objective push-type sleep feedback messages to improve their sleep hours for a subset of participants in study 1 (n=81). The feedback messages were generated based on their sleep data measured on previous nights and were randomly sent to participants with a 50% chance for each day (microrandomization).
RESULTS
In study 1, we applied hierarchical clustering to dichotomize the population into 2 clusters (group A and group B) and found that group B was characterized by unstable habitual sleep behaviors (large intraindividual variabilities). In addition, linear mixed-effect models showed that the interindividual variability of sleep hours was significantly associated with depressive mood (β=3.83; P=.004), anxiety (β=5.70; P=.03), and subjective sleep quality (β=-3.37; P=.03). In study 2, we found that providing sleep feedback prolonged subsequent sleep hours (increasing up to 40 min; P=.01), and this effect lasted for up to 7 days. Overall, the stability of sleep hours in study 2 was significantly improved among participants in group B compared with the participants in study 1 (P=.001).
CONCLUSIONS
This is the first study to demonstrate that providing sleep feedback can benefit the modification of habitual sleep behaviors in a microrandomized trial. The findings of this study encourage the use of digitalized health intervention that uses real-time health monitoring and personalized feedback.
背景
睡眠障碍是导致未来健康和职业问题的主要因素。移动健康可以为处于脆弱健康状态的个体提供干预措施,以解决现实环境中的不良健康行为(即时自适应干预)。
目的
本研究旨在确定日常生活中处于脆弱睡眠状态的亚人群(研究 1),并通过微随机试验(研究 2)测试提供移动健康干预是否能改善现实环境中的习惯性睡眠行为和心理健康。
方法
日本工人(n=182)被指示使用数字设备在现实环境中收集习惯性睡眠行为和即时症状(包括抑郁情绪、焦虑和主观睡眠质量)的数据。在研究 1 中,我们计算了睡眠小时、睡眠中点和睡眠效率的个体内平均值和变异性,以描述他们的习惯性睡眠行为。在研究 2 中,我们设计并进行了睡眠即时自适应干预,为研究 1 中的一部分参与者(n=81)提供客观的推送式睡眠反馈信息,以改善他们的睡眠小时数。反馈信息是基于他们前一晚测量的睡眠数据生成的,并以 50%的概率随机发送给参与者(微随机化)。
结果
在研究 1 中,我们应用层次聚类将人群分为 2 组(A 组和 B 组),发现 B 组的习惯性睡眠行为不稳定(个体内变异性大)。此外,线性混合效应模型显示,睡眠小时的个体间变异性与抑郁情绪(β=3.83;P=.004)、焦虑(β=5.70;P=.03)和主观睡眠质量(β=-3.37;P=.03)显著相关。在研究 2 中,我们发现提供睡眠反馈可以延长随后的睡眠时间(最多增加 40 分钟;P=.01),并且这种效果可以持续长达 7 天。总体而言,与研究 1 中的参与者相比,B 组参与者的睡眠小时稳定性在研究 2 中得到了显著改善(P=.001)。
结论
这是第一项表明提供睡眠反馈可以在微随机试验中有益于习惯性睡眠行为修正的研究。这项研究的结果鼓励使用实时健康监测和个性化反馈的数字化健康干预。