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中低位直肠癌髂内和闭孔淋巴结的处理。

Management of internal iliac and obturator lymph nodes in mid-low rectal cancer.

机构信息

Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.

Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, 68198, Omaha, Nebraska, USA.

出版信息

World J Surg Oncol. 2024 Jun 12;22(1):153. doi: 10.1186/s12957-024-03427-0.

Abstract

In rectal cancer treatment, the diagnosis and management of lateral pelvic lymph nodes (LLN) are critical for preventing local recurrence. Over time, scholars have reached a consensus: when imaging suggests LLN metastasis, combining neoadjuvant chemoradiotherapy (nCRT) with selective LLN dissection (LLND) can mitigate the risk of recurrence. Selective LLND typically encompasses lymph nodes in the internal iliac and obturator regions. Recent studies emphasize distinctions between internal iliac and obturator lymph nodes regarding prognosis and treatment outcomes, prompting the need for differentiated diagnostic and treatment approaches.

摘要

在直肠癌治疗中,侧方骨盆淋巴结(LLN)的诊断和管理对于预防局部复发至关重要。随着时间的推移,学者们已经达成共识:当影像学提示 LLN 转移时,将新辅助放化疗(nCRT)与选择性 LLN 解剖(LLND)相结合可以降低复发风险。选择性 LLND 通常包括髂内和闭孔区域的淋巴结。最近的研究强调了髂内和闭孔淋巴结在预后和治疗结果方面的区别,这促使我们需要采用差异化的诊断和治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e0c4/11167753/77716a053487/12957_2024_3427_Fig1_HTML.jpg

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