Division of Surgical Oncology, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Department of Surgery, Enloe Medical Center, Chico, California, USA.
J Surg Oncol. 2023 Jun;127(8):1264-1270. doi: 10.1002/jso.27317.
Lateral pelvic lymph node (LPLN) involvement occurs in 10%-25% of rectal cancer cases. Total mesorectal excision (TME) with routine LPLN dissection (LPLND) is predominantly applied in Japan whereas TME with neoadjuvant treatment are used in the West. LPLND is a morbid procedure and minimally invasive techniques may help reduce its morbidity. Selective lateral pelvic node dissection with TME following neoadjuvant treatment achieves acceptable disease-free and overall survival.
侧方骨盆淋巴结（LPLN）转移发生于 10%-25%的直肠癌病例中。在日本，直肠系膜全切除（TME）联合常规 LPLN 清扫（LPLND）被广泛应用，而在西方，TME 联合新辅助治疗更为常见。LPLND 是一种创伤较大的术式，微创技术可能有助于降低其并发症发生率。新辅助治疗后 TME 联合选择性侧方骨盆淋巴结清扫术可获得可接受的无病生存率和总生存率。
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