Department of Pediatrics Gastroenterology, Ganzhou Women and Children's Health Care Hospital, 341000 Ganzhou, Jiangxi, China.
Department of Medical Records Management, Ganzhou Women and Children's Health Care Hospital, 341000 Ganzhou, Jiangxi, China.
Actas Esp Psiquiatr. 2024 Jun;52(3):248-255. doi: 10.62641/aep.v52i3.1642.
Maternal depression may have negative impacts on children's behavior and mental health. Childhood food allergy is a common health issue, yet its relationship with maternal depression remains incompletely understood. This study aimed to analyze the association between children's food allergy symptoms and maternal depression through cross-sectional and cohort studies.
This study selected a total of 580 children with food allergy and their mothers who met the inclusion criteria in Ganzhou Women and Children's Health Care Hospital from April 2015 to April 2022, evaluated the symptom levels of children's food allergy according to the guidelines, assessed the depressive symptoms of mothers using self-rating depression scale (SDS), and analyzed the relationship between the symptom severity of children's food allergy and the risk of maternal depression; at the same time, one-year follow-up of mothers without depression was carried out to measure the incidence of depression to further explore this relationship.
The 580 children with food allergies in the cross-sectional study consisted of 365 (62.93%) males and 215 (37.07%) females, aged (8.98 ± 2.30) years, with 298 (51.37%) experiencing Level-Ⅰ, and 282 (48.63%) experiencing Level-Ⅱ. A total of 56 (9.66%) mothers suffered from depression, aged (42.74 ± 5.42) years. Adjusting for confounders including mother's age, education level, marital status, family income, comorbidities, history of allergies, family history of food allergies, history of psychiatric disorders, current smoking status, current alcohol consumption, current regular exercise status, childhood food allergens and food allergy categorization, the mothers of children with child food allergy symptom Level-Ⅱ were found to have a higher risk of depression compared with mothers with child food allergy symptom Level-Ⅰ, odds ratio (OR) = 2.025 (95% confidence interval (CI): 1.319-3.128, p = 0.001). In the one-year cohort study, 38 (7.25%) mothers had new-onset depressive symptoms. Mothers of children with a child food allergy symptom Level-Ⅱ had an OR = 2.165 (95% CI: 1.612-2.902, p < 0.001) for depressive symptoms compared to mothers with a child food allergy symptom Level-Ⅰ.
Among children with food allergy symptom scores of Level-Ⅰ and Level-Ⅱ, higher levels were associated with a higher prevalence of depression in their mothers.
母亲的抑郁可能对儿童的行为和心理健康产生负面影响。儿童食物过敏是一种常见的健康问题，但它与母亲抑郁之间的关系仍不完全清楚。本研究旨在通过横断面和队列研究分析儿童食物过敏症状与母亲抑郁之间的关系。
本研究共选择了 2015 年 4 月至 2022 年 4 月在赣州市妇幼保健院符合纳入标准的 580 名食物过敏儿童及其母亲，根据指南评估儿童食物过敏症状水平，采用自评抑郁量表（SDS）评估母亲的抑郁症状，并分析儿童食物过敏症状严重程度与母亲抑郁风险的关系；同时对无抑郁的母亲进行为期一年的随访，以测量抑郁发生率，进一步探讨这种关系。
在横断面研究中，580 名食物过敏儿童中，男性 365 名（62.93%），女性 215 名（37.07%），年龄（8.98±2.30）岁，其中Ⅰ级 298 名（51.37%），Ⅱ级 282 名（48.63%）。共有 56 名（9.66%）母亲患有抑郁症，年龄（42.74±5.42）岁。在调整母亲年龄、教育水平、婚姻状况、家庭收入、合并症、过敏史、食物过敏家族史、精神疾病史、当前吸烟状况、当前饮酒状况、当前定期运动状况、儿童食物过敏原和食物过敏分类等混杂因素后，发现儿童食物过敏症状水平Ⅱ级的母亲发生儿童食物过敏症状的风险高于儿童食物过敏症状水平Ⅰ级的母亲，比值比（OR）=2.025（95%置信区间（CI）：1.319-3.128，p=0.001）。在为期一年的队列研究中，有 38 名（7.25%）母亲出现新发抑郁症状。与儿童食物过敏症状水平Ⅰ级的母亲相比，儿童食物过敏症状水平Ⅱ级的母亲发生抑郁的 OR=2.165（95%CI：1.612-2.902，p<0.001）。
在儿童食物过敏症状水平为Ⅰ级和Ⅱ级的儿童中，较高的水平与母亲抑郁的发生率较高相关。
