M'Buyamba-Kabangu J R, Fagard R, Lijnen P, Amery A
Eur J Appl Physiol Occup Physiol. 1985;53(4):304-7. doi: 10.1007/BF00422843.
The relationship between plasma renin activity (PRA) at rest and physical fitness was studied in 40 normal young subjects on a liberal sodium intake. Plasma renin activity was measured in arterial blood withdrawn at the end of a 30-min period of rest in recumbency, while physical fitness was expressed by the highest oxygen uptake achieved during an uninterrupted graded exercise test performed in the sitting position on an electromagnetically braked ergometer bicycle (peak VO2). Log PRA correlated significantly and inversely with peak VO2 adjusted for body weight (r = -0.34; P less than 0.05) in single regression analysis. Using multiple regression and adjusted peak VO2, age, urinary sodium excretion and mean intra-arterial pressure as independent variables, no combination of two or more independent variables yielded significant partial correlation coefficients with log PRA. This correlation suggests that PRA at rest is inversely related to the subject's physical fitness.
在40名钠摄入正常的年轻受试者中，研究了静息状态下血浆肾素活性（PRA）与身体素质之间的关系。在受试者卧位休息30分钟结束时采集动脉血，测定血浆肾素活性，而身体素质则通过在电磁制动测力计自行车上坐位进行的不间断分级运动试验中达到的最高摄氧量来表示（峰值VO2）。在单因素回归分析中，经体重校正后的log PRA与峰值VO2呈显著负相关（r = -0.34；P < 0.05）。以多元回归分析并将校正后的峰值VO2、年龄、尿钠排泄量和平均动脉压作为自变量，没有两个或更多自变量的组合与log PRA产生显著的偏相关系数。这种相关性表明，静息状态下的PRA与受试者的身体素质呈负相关。
