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视力丧失作为维生素B12缺乏的首发症状

Vision Loss as a Presenting Symptom of Vitamin B12 Deficiency.

作者信息

Othman Izzati, Tai Evelyn, Kuganasan Sangeeta, Abu Norlelawati

机构信息

Department of Ophthalmology, Hospital Tuanku Jaafar Seremban, Negeri Sembilan, MYS.

Department of Ophthalmology and Visual Science, Hospital Universiti Sains Malaysia, Kubang Kerian, MYS.

出版信息

Cureus. 2024 May 11;16(5):e60113. doi: 10.7759/cureus.60113. eCollection 2024 May.

Abstract

Nutritional optic neuropathy is a rare and often overlooked factor leading to bilateral, symmetrical, and gradual visual impairment. This condition falls within the category of metabolic neuropathies. We documented a case involving bilateral nutritional optic neuropathy attributed to pancytopenia associated with vitamin B12 deficiency. A healthy 65-year-old Indian woman reported a bilateral, progressive, painless decline in vision over the past six months. She had a history of reduced oral intake for the preceding year and denied experiencing any gastrointestinal or constitutional symptoms. Bilateral visual acuity was 1/60. Examination revealed pale optic discs with attenuated vessels in both eyes and a cup-disc ratio of 0.3. The blood analysis showed low indices and a deficiency in serum vitamin B12. Despite undergoing treatment, her vision remained impaired due to the chronic nature of the condition. This case highlights the importance of identifying visual symptoms in an elderly woman experiencing malnutrition caused by inadequate dietary habits, which leads to bilateral nutritional optic neuropathy.

摘要

营养性视神经病变是一种罕见且常被忽视的导致双侧、对称性、渐进性视力损害的因素。这种病症属于代谢性神经病变范畴。我们记录了一例因全血细胞减少伴维生素B12缺乏导致的双侧营养性视神经病变病例。一名65岁健康的印度女性报告称,在过去六个月里双眼视力呈双侧、进行性、无痛性下降。她有前一年口服摄入量减少的病史,否认有任何胃肠道或全身性症状。双眼视力均为1/60。检查发现双眼视盘苍白,血管变细,杯盘比为0.3。血液分析显示指标偏低且血清维生素B12缺乏。尽管接受了治疗,但由于病情的慢性性质,她的视力仍然受损。该病例凸显了在因饮食习惯不良导致营养不良的老年女性中识别视觉症状的重要性,这种营养不良会导致双侧营养性视神经病变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dae2/11164691/b6de111416ae/cureus-0016-00000060113-i01.jpg

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