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减肥手术后的营养性视神经病变。

Nutritional optic neuropathy following bariatric surgery.

作者信息

Sawicka-Pierko Anna, Obuchowska Iwona, Hady Razak Hady, Mariak Zofia, Dadan Jacek

机构信息

Department of Ophthalmology, Medical University of Bialystok, Bialystok, Poland.

1 Clinical Department of General and Endocrine Surgery, Medical University of Bialystok, Bialystok, Poland.

出版信息

Wideochir Inne Tech Maloinwazyjne. 2014 Dec;9(4):662-6. doi: 10.5114/wiitm.2014.47262. Epub 2014 Nov 28.

Abstract

Bariatric procedures, associated with gastrointestinal malabsorption of vitamins and microelements, may constitute a risk factor for nutritional optic neuropathy (NON). We present a case of a 34-year-old female patient who developed bilateral NON after sleeve gastrectomy. Despite postoperative ophthalmological supervision, 10 months after the procedure the woman presented with a bilateral decrease in visual acuity down to 0.8, bilateral visual field loss and abnormal visual evoked potential recordings. Laboratory abnormalities included decreased serum concentration of vitamin B12 (161 pg/ml). Treatment was based on intramuscular injections of vitamin B12 (1000 units per day). After 1 week of the treatment, we observed more than a three-fold increase in the serum concentration of vitamin B12 and resolution of the bilateral symptoms of NON. The incidence of NON is likely to increase due to the growing number of these bariatric procedures performed worldwide. Therefore, all persons subjected to such surgery should receive long-term ophthalmological follow-up and supplementation with vitamins and microelements.

摘要

减肥手术与维生素和微量元素的胃肠道吸收不良有关,可能构成营养性视神经病变(NON)的一个危险因素。我们报告一例34岁女性患者,她在接受袖状胃切除术后发生了双侧NON。尽管术后进行了眼科监测,但术后10个月,该女性出现双侧视力下降至0.8、双侧视野缺损以及视觉诱发电位记录异常。实验室检查异常包括血清维生素B12浓度降低(161 pg/ml)。治疗基于肌肉注射维生素B12(每天1000单位)。治疗1周后,我们观察到血清维生素B12浓度增加了三倍多,且双侧NON症状得到缓解。由于全球范围内此类减肥手术的数量不断增加,NON的发病率可能会上升。因此,所有接受此类手术的人都应接受长期眼科随访,并补充维生素和微量元素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b304/4280430/41dab42700b5/WIITM-9-24066-g001.jpg

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