de Silva Punyanganie, Jayamanne Gerard, Bolton Robin
Doncaster Royal Infirmary, Doncaster, UK.
J Med Case Rep. 2008 Sep 10;2:299. doi: 10.1186/1752-1947-2-299.
Nutritional optic neuropathies are uncommon and can be associated with gradual visual loss and optic atrophy or sudden vision loss and optic disc swelling.
A 44-year-old woman presented with a 4-week history of progressive visual loss and was noted to have bilateral retrobulbar optic neuropathy. No other clinical abnormality was noted. Investigations revealed severe folate deficiency with normal vitamin B12 levels. Her alcohol and tobacco consumption was moderate and subsequent correction of folate levels with oral supplementation has led to improvement in her visual acuity.
This case highlights an unusual presentation of folic acid deficiency that may present to the general physician.
营养性视神经病变并不常见,可能与视力逐渐丧失和视神经萎缩有关,也可能与视力突然丧失和视盘肿胀有关。
一名44岁女性,有4周进行性视力丧失病史,被诊断为双侧球后视神经炎。未发现其他临床异常。检查发现严重叶酸缺乏,维生素B12水平正常。她的烟酒摄入量适中,随后通过口服补充剂纠正叶酸水平后,视力有所改善。
本病例突出了叶酸缺乏一种不寻常的表现,可能会出现在普通内科医生面前。