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人群健康干预对高血压控制差异的影响:一项阶梯式楔形集群随机临床试验。

Effectiveness of a Population Health Intervention on Disparities in Hypertension Control: A Stepped Wedge Cluster Randomized Clinical Trial.

机构信息

Division of General Internal Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Devoted Health, Waltham, MA, USA.

出版信息

J Gen Intern Med. 2024 Nov;39(15):3028-3034. doi: 10.1007/s11606-024-08839-y. Epub 2024 Jun 12.

Abstract

BACKGROUND

Disparities in hypertension control across race, ethnicity, and language have been a long-standing problem in the United States.

OBJECTIVE

To assess whether a multi-pronged intervention can improve hypertension control for a target population and reduce disparities.

DESIGN

This stepped wedge cluster randomized trial was conducted at 15 adult primary care clinics affiliated with Massachusetts General Hospital. PCPs were randomized to receive the intervention in twelve groups.

PARTICIPANTS

The target population was patients who met one of the following criteria based on self-identification: (1) Asian, Black, Indigenous, multi-racial, or other race; (2) Hispanic ethnicity; or (3) preferred language other than English. Reference population was White, English-speaking patients.

INTERVENTIONS

PCPs were given access to an online equity dashboard that displays disparities in chronic disease management and completed an equity huddle with population health coordinators (PHCs), which involved reviewing target patients whose hypertension was not well controlled. In addition, community health workers (CHWs) were available in some practices to offer additional support.

MAIN MEASURES

The primary outcome was change in the proportion of target patients meeting the hypertension control goal when comparing intervention and control periods.

KEY RESULTS

Of the 365 PCPs who were randomized, 311 PCPs and their 10,865 target patients were included in the analysis. The intervention led to an increase in hypertension control in the target population (RD 0.9%; 95% CI [0.3,1.5]) and there was a higher intervention effect in the target population compared to the reference population (DiD 2.1%; 95% CI [1.1, 3.1]).

CONCLUSIONS

Utilizing data on disparities in quality outcome measures in routine clinical practice augmented by clinical support provided by PHCs and CHWs led to modest, but statistically significant, improvement in hypertension control among BIPOC, Hispanic, and LEP patients.

TRIAL REGISTRATION

ClinicalTrials.gov Identifier: NCT05278806.

摘要

背景

在美国,不同种族、族裔和语言的高血压控制存在差异,这是一个长期存在的问题。

目的

评估多管齐下的干预措施是否可以改善目标人群的高血压控制并减少差异。

设计

这是一项在马萨诸塞州综合医院附属的 15 家成人初级保健诊所进行的阶梯式楔形群随机试验。初级保健医生被随机分为 12 组接受干预。

参与者

目标人群是根据自我认同符合以下标准之一的患者:(1)亚裔、黑人、原住民、多种族或其他种族;(2)西班牙裔;或(3)首选语言不是英语。参考人群是白人、英语患者。

干预措施

初级保健医生可以访问一个在线公平仪表板,该仪表板显示慢性病管理方面的差异,并与人口健康协调员(PHC)进行公平小组讨论,其中包括审查高血压控制不佳的目标患者。此外,一些诊所还配备了社区卫生工作者(CHW)以提供额外支持。

主要措施

主要结果是比较干预期和对照组时,符合高血压控制目标的目标患者比例的变化。

主要结果

在随机分配的 365 名初级保健医生中,有 311 名初级保健医生及其 10865 名目标患者纳入了分析。干预措施导致目标人群的高血压控制率提高(RD 0.9%;95%CI [0.3,1.5]),并且与参考人群相比,目标人群的干预效果更高(DiD 2.1%;95%CI [1.1, 3.1])。

结论

利用常规临床实践中质量结果测量的差异数据,并辅以 PHC 和 CHW 提供的临床支持,导致 BIPOC、西班牙裔和 LEP 患者的高血压控制有适度但具有统计学意义的改善。

试验注册

ClinicalTrials.gov 标识符:NCT05278806。

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