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10-羟基癸酸、反式-10-羟基-2-癸酸和癸二酸:来源、代谢以及潜在的健康功能和营养应用。

10-hydroxy decanoic acid, trans-10-hydroxy-2-decanoic acid, and sebacic acid: Source, metabolism, and potential health functionalities and nutraceutical applications.

机构信息

Food Technology Division, School of Industrial Technology, Universiti Sains Malaysia, Gelugor, Penang, Malaysia.

Applied Science Research Center, Applied Science Private University, Amman, Jordan.

出版信息

J Food Sci. 2024 Jul;89(7):3878-3893. doi: 10.1111/1750-3841.17143. Epub 2024 Jun 12.

DOI:10.1111/1750-3841.17143
PMID:38865248
Abstract

The popularity of royal jelly (RJ) as a functional food has attracted attention from various industries, especially nutraceuticals, due to the increasing demand from health enthusiasts. Sebacic acid, 10-hydroxy decanoic acid, and trans-10-hydroxy-2-decanoic acid are the primary medium-chain fatty acids (MCFAs) within RJ responsible for their health benefits. This review aims to consolidate information on these MCFAs' metabolic relationship and health functionalities in nutraceutical applications. We also investigated the natural characteristics mediated by these MCFAs and their metabolism in organisms. Finally, the production of these MCFAs using conventional (from castor oil) and alternative (from RJ) pathways was also discussed. This review can be a reference for using them as functional ingredients in nutraceutical industries.

摘要

蜂王浆(RJ)作为一种功能性食品的流行引起了各个行业的关注,特别是营养保健品行业,因为健康爱好者的需求不断增加。癸酸、10-羟基癸酸和反式-10-羟基-2-癸酸是 RJ 中主要的中链脂肪酸(MCFAs),它们对其健康益处负责。本综述旨在整合这些 MCFAs 在营养保健品应用中的代谢关系和健康功能方面的信息。我们还研究了这些 MCFAs 在生物体中的天然特性及其代谢。最后,还讨论了使用这些 MCFAs 的常规(来自蓖麻油)和替代(来自 RJ)途径进行生产。本综述可作为在营养保健品行业中将它们用作功能性成分的参考。

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J Food Sci. 2024 Jul;89(7):3878-3893. doi: 10.1111/1750-3841.17143. Epub 2024 Jun 12.
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