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首例肺内孤立性空洞性结节病伴马内分枝杆菌感染报告。

First report of solitary cavitation nodules in the lungs with Mycobacterium canariasense.

机构信息

The Affiliated Infectious Diseases Hospital of Soochow University, The Fifth People's Hospital of Suzhou, Suzhou 215000, Jiangsu, China.

出版信息

J Infect Dev Ctries. 2024 May 30;18(5):826-828. doi: 10.3855/jidc.18535.

DOI:10.3855/jidc.18535
PMID:38865393
Abstract

INTRODUCTION

Mycobacterium canariasense is a relatively rare and rapidly growing nontuberculous mycobacterium (NTM) infection.

CASE REPORT

This case report describes a 36-year-old man with a Canariasense infection in the lung with solitary cavitation nodules located subpleural on CT scan, for which the final diagnosis was made by metagenomic next-generation sequencing (mNGS) of bronchoalveolar lavage fluid (BALF-mNGS). It was successfully treated with levofloxacin and amikacin.

CONCLUSIONS

This experience is instructive because clinical diagnostic and CT imaging characteristics and treatment strategy guidelines for pulmonary infections caused by M. canariasense have not yet been established.

摘要

简介

海分枝杆菌是一种相对罕见且生长迅速的非结核分枝杆菌(NTM)感染。

病例报告

本病例报告描述了一例 36 岁男性患有肺海分枝杆菌感染,CT 扫描显示位于胸膜下的孤立性空洞性结节,最终诊断通过支气管肺泡灌洗液(BALF-mNGS)的宏基因组下一代测序(mNGS)得出。该患者经左氧氟沙星和阿米卡星治疗后痊愈。

结论

本经验具有指导意义,因为尚未制定海分枝杆菌引起的肺部感染的临床诊断和 CT 成像特征及治疗策略指南。

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