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犬猫电化学疗法——综述

Electrochemotherapy in dogs and cats-A review.

作者信息

Ramos Sofia Chichorro, Dias-Pereira Patrícia, Luís Ana Lúcia, MacFarlane Michael, Santos Andreia Alexandra

机构信息

Oncology Service, North Downs Specialist Referrals, Bletchingley, UK.

Institute of Biomedical Sciences Abel Salazar, Porto, Portugal.

出版信息

Vet Comp Oncol. 2024 Sep;22(3):311-321. doi: 10.1111/vco.12980. Epub 2024 Jun 12.

Abstract

Electrochemotherapy (ECT) is a treatment modality that combines the electroporation of cell membranes with chemotherapy to facilitate the transport of non-permeant molecules into cells. Several canine and feline studies have shown promising results, suggesting that ECT can be a valid adjuvant or alternative treatment option for some tumours. The objective of this paper is to provide a bibliographic review of the principles and applications of ECT in veterinary medicine and to compare to its use in human medicine.

摘要

电化学疗法(ECT)是一种将细胞膜电穿孔与化疗相结合的治疗方式,以促进非渗透性分子进入细胞。多项犬猫研究已显示出有前景的结果,表明ECT对某些肿瘤可以是一种有效的辅助或替代治疗选择。本文的目的是提供一份关于ECT在兽医学中的原理和应用的文献综述,并将其与在人类医学中的应用进行比较。

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