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纳米疫苗的知识版图:基于文献计量学的科学进展与未来方向

The Intellectual Landscape of Nanovaccines: A Bibliometric Perspective on Scientific Progress and Future Directions.

作者信息

Jose Jobin, M N Vinoj, R G Bindu, Jose Anat Suman, Jubin Jacob

机构信息

Library, Marian College Kuttikkanam (Autonomous), Kuttikkanam, IND.

Physics, St. Peter's College, Kolenchery, Kolenchery, IND.

出版信息

Cureus. 2024 May 12;16(5):e60131. doi: 10.7759/cureus.60131. eCollection 2024 May.

Abstract

This bibliometric study provides a comprehensive analysis of the burgeoning field of nanovaccine research, leveraging data sourced from Scopus and employing the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) flowchart for the meticulous screening, inclusion, and exclusion of relevant studies. Utilizing sophisticated bibliometric tools, such as Biblioshiny and CiteSpace, we dissected the expansive literature to unearth critical insights into the annual scientific output, identifying key contributors and pivotal publications that have shaped the domain. The analysis delineates the most influential authors, sources, and globally cited documents, offering a macroscopic view of the field's intellectual structure and growth trajectory. Trend topics and thematic mapping underscored the evolution of research foci, from fundamental immunological mechanisms to cutting-edge nanomaterial applications. Factorial analysis and keyword co-occurrence networks revealed the intricate associations and thematic concentrations within the literature. The study's robust methodology also pinpointed the keywords exhibiting the strongest citation bursts, signifying emergent areas of intense academic interest. Networks of cited authors illuminated collaborative patterns among scholars, while timeline network visualizations of country collaborations depicted the global interplay in nanovaccine development. Crucially, this study identified notable research gaps and practical implications, suggesting directions for future investigation and highlighting the translational potential of nanovaccines in public health and personalized medicine. This bibliometric investigation not only maps the current landscape but also charts a course for the trajectory of nanovaccine research, emphasizing its role as a cornerstone of innovative immunotherapeutic strategies.

摘要

这项文献计量学研究对新兴的纳米疫苗研究领域进行了全面分析,利用来自Scopus的数据,并采用系统评价和Meta分析的首选报告项目(PRISMA)流程图对相关研究进行细致筛选、纳入和排除。我们使用了复杂的文献计量工具,如Biblioshiny和CiteSpace,剖析了大量文献,以挖掘有关年度科学产出的关键见解,确定了塑造该领域的关键贡献者和重要出版物。分析描绘了最具影响力的作者、来源和全球被引用的文献,提供了该领域知识结构和发展轨迹的宏观视角。趋势主题和主题映射突出了研究重点的演变,从基本免疫机制到前沿纳米材料应用。因子分析和关键词共现网络揭示了文献中的复杂关联和主题集中情况。该研究强大的方法还确定了表现出最强引用爆发的关键词,表明了学术界强烈关注的新兴领域。被引用作者网络阐明了学者之间的合作模式,而国家合作的时间线网络可视化描绘了纳米疫苗开发中的全球互动。至关重要的是,这项研究确定了显著的研究差距和实际意义,为未来的研究指明了方向,并突出了纳米疫苗在公共卫生和个性化医学中的转化潜力。这项文献计量学调查不仅描绘了当前的格局,还为纳米疫苗研究的轨迹规划了路线,强调了其作为创新免疫治疗策略基石的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fd5a/11167401/393f17136228/cureus-0016-00000060131-i01.jpg

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