Department of Psychiatry, Liupanshui Third People's Hospital, Guizhou, P.R. China.
Department of Rehabilitation, Liupanshui Third People's Hospital, Guizhou, P.R. China.
J Investig Med. 2024 Oct;72(7):737-746. doi: 10.1177/10815589241261286. Epub 2024 Jul 30.
The prevalence of depression continues to rise, and it has a high death and disability rate. Life's Essential 8 (LE8) is an updated measurement of cardiovascular health (CVH), and a higher score of LE8 represents healthier CVH. Our study aimed to investigate the association between the LE8 and depression among adults. This cross-sectional study used data from the National Health and Nutrition Examination Survey. CVH was measured by using LE8 according to American Heart Association definitions. Depression was assessed by the 9-item Patient Health Questionnaire (PHQ-9). Weighted univariable and multivariable logistic analyses were performed to investigate the association of LE8 with depression. Subgroup analyses were also conducted in different groups based on age, gender, race, body mass index (BMI), smoking, arthritis, cardiovascular disease, and chronic kidney disease. A total of 22,149 participants were included in the database, with a mean LE8 score of 71.27. The prevalence of depression was 7.32%. The mean scores of LE8 in health behaviors and health factors were 73.28 and 69.26, respectively. After adjustment of potential confounders, a higher LE8 score was associated with lower odds of depression (odds ratio = 0.27, 95% confidence interval: 0.20-0.37). A similar association was observed in the subgroup analyses. Higher overall LE8 scores and higher scores for each component (diet, physical activity, nicotine exposure, sleep duration, BMI, blood lipids, blood glucose, and blood pressure) were associated with lower odds of depression. LE8 score might be a useful tool for both cardiologists and psychiatrists in screening for and monitoring physical and mental health. Primary care physicians also could better tailor care and interventions to address both physical and mental health needs.
抑郁症的患病率持续上升，且其死亡率和致残率较高。生活的基本 8 项（LE8）是心血管健康（CVH）的最新衡量标准，较高的 LE8 得分表示 CVH 更健康。我们的研究旨在探讨 LE8 与成年人抑郁之间的关系。本横断面研究使用了来自全国健康和营养检查调查的数据。根据美国心脏协会的定义，使用 LE8 来衡量 CVH。通过 9 项患者健康问卷（PHQ-9）评估抑郁。进行加权单变量和多变量逻辑分析，以调查 LE8 与抑郁之间的关联。还根据年龄、性别、种族、体重指数（BMI）、吸烟、关节炎、心血管疾病和慢性肾病在不同组中进行了亚组分析。数据库共纳入 22149 名参与者，平均 LE8 评分为 71.27。抑郁症的患病率为 7.32%。健康行为和健康因素的 LE8 平均得分分别为 73.28 和 69.26。在调整了潜在混杂因素后，较高的 LE8 评分与较低的抑郁几率相关（比值比=0.27，95%置信区间：0.20-0.37）。亚组分析也观察到了类似的关联。较高的总体 LE8 评分和每个组成部分（饮食、体力活动、尼古丁暴露、睡眠时间、BMI、血脂、血糖和血压）的得分与较低的抑郁几率相关。LE8 评分可能是心脏病专家和精神科医生筛查和监测身心健康的有用工具。初级保健医生也可以更好地调整护理和干预措施，以满足身体和心理健康需求。
