Department of Anesthesiology, The Second People's Hospital of Wuhu, Wuhu, Anhui, China.
Department of Anesthesiology, The Second People's Hospital of Wuhu, Wuhu, Anhui, China -
Minerva Anestesiol. 2024 Jun;90(6):520-529. doi: 10.23736/S0375-9393.24.17927-8.
To investigate the non-inferiority of ultrasound-guided rhomboid intercostal and subserratus plane (RISS) block compared to thoracic paravertebral block (TPVB) in postoperative analgesia for thoracoscopic surgeries.
This study consecutively enrolled 50 patients undergoing elective thoracoscopic surgery. Following general anesthesia, the RISS group received a unilateral block with 40 mL of 0.25% ropivacaine, while the TPVB group received with 30 mL of 0.33% ropivacaine. The primary outcome measure was the 24-hour postoperative resting VAS score. Secondary outcome measures included nerve block operation time for two groups, postoperative 1, 2, 4, 8, 48-hour resting VAS scores, and different time points coughing VAS scores, time to first postoperative ambulation, total intravenous analgesic consumption at different time points postoperatively, complications related to the block.
There were no significant statistical differences between the two groups in terms of postoperative rest and cough VAS scores at each time (P>0.05), and the mean difference in rest VAS scores did not exceed the non-inferiority margin in 95% CI. There were no significant differences in total intraoperative and postoperative analgesic consumption at different time points (P>0.05), and no significant differences in time to first postoperative ambulation (P>0.05). Compared to the TPVB group, the RISS group had a shorter nerve block operation time (259.43±30.11 vs. 335.23±30.96 s, P<0.001) and fewer instances of intraoperative hypotension (two vs. seven cases, P=0.022), bleeding at the puncture site, pneumothorax, and arrhythmia.
In thoracoscopic surgeries, the postoperative analgesic efficacy of ultrasound-guided RISS block is not inferior to TPVB. Compared to TPVB, RISS block is simpler, quicker, and associated with fewer puncture-related complications.
本研究旨在探究超声引导下肋缘间和肋间肌平面(RISS)阻滞与胸椎旁神经阻滞(TPVB)在胸腔镜手术后镇痛效果方面的非劣效性。
本研究连续纳入 50 例行择期胸腔镜手术的患者。全身麻醉后,RISS 组接受单侧阻滞,注入 40ml0.25%罗哌卡因;TPVB 组接受 30ml0.33%罗哌卡因。主要观察指标为术后 24 小时静息 VAS 评分。次要观察指标包括两组神经阻滞操作时间、术后 1、2、4、8、48 小时静息 VAS 评分、不同时间点咳嗽 VAS 评分、术后首次下床活动时间、术后不同时间点静脉镇痛总消耗量、与阻滞相关的并发症。
两组患者术后各时间点静息和咳嗽 VAS 评分差异均无统计学意义(P>0.05),且在 95%CI 置信区间内,静息 VAS 评分的均值差值未超过非劣效性边界。两组患者在不同时间点静脉镇痛总消耗量差异均无统计学意义(P>0.05),术后首次下床活动时间差异亦无统计学意义(P>0.05)。与 TPVB 组相比,RISS 组神经阻滞操作时间更短(259.43±30.11 比 335.23±30.96s,P<0.001),术中低血压发生率更低(2 例比 7 例,P=0.022),穿刺部位出血、气胸和心律失常的发生率更低。
在胸腔镜手术中,超声引导下 RISS 阻滞的术后镇痛效果不劣于 TPVB。与 TPVB 相比,RISS 阻滞操作更简单、更迅速,且与穿刺相关的并发症更少。