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一例严重高钠血症患者的允许性低血压:病例报告

Permissive Hypotension in a Patient with Severe Hypernatremia: A Case Report.

作者信息

Hlady Andrea, Kerner David, Walker Laura E

机构信息

Mayo Clinic Health System, Department of Emergency Medicine, Alberta Lea, Minnesota.

Mayo Clinic, Department of Emergency Medicine, Rochester, Minnesota.

出版信息

Clin Pract Cases Emerg Med. 2024 May;8(2):133-137. doi: 10.5811/cpcem.1422.

DOI:10.5811/cpcem.1422
PMID:38869336
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11166063/
Abstract

INTRODUCTION

Severe hypernatremia is a critical situation, and when coupled with intravascular depletion and hypotension can create a treatment dilemma.

CASE REPORT

We present the case of a medically complex patient who had gradually worsening alteration of mental status and mean arterial pressures in the 50s on presentation to the emergency department.

CONCLUSION

Final diagnoses included severe hypernatremia and hypovolemic shock secondary to poor oral intake. We used judicious fluid repletion with gradual improvement in sodium levels and permissive hypotension to avoid rapid osmotic shifts. Balancing reperfusion and the risk for osmotic effects of aggressive fluid resuscitation can be a challenging situation for the multidisciplinary team.

摘要

引言

严重高钠血症是一种危急情况,当与血管内液体缺失和低血压同时出现时,会造成治疗困境。

病例报告

我们呈现了一名患有多种复杂疾病的患者的病例,该患者在急诊就诊时精神状态逐渐恶化,平均动脉压处于50多。

结论

最终诊断包括严重高钠血症和因口服摄入不足继发的低血容量性休克。我们谨慎地进行液体补充,使钠水平逐渐改善,并采用允许性低血压以避免快速的渗透压变化。对于多学科团队而言,平衡再灌注与积极液体复苏的渗透压效应风险可能是一个具有挑战性的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb9f/11166063/bf97d4a16ecb/cpcem-8-133-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb9f/11166063/bf97d4a16ecb/cpcem-8-133-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb9f/11166063/bf97d4a16ecb/cpcem-8-133-g001.jpg

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本文引用的文献

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Permissive Hypotension vs. Conventional Resuscitation in Patients With Trauma or Hemorrhagic Shock: A Review.创伤或失血性休克患者的允许性低血压与传统复苏:综述
Cureus. 2021 Jul 19;13(7):e16487. doi: 10.7759/cureus.16487. eCollection 2021 Jul.
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Risk Factors for Delirium in Older Adults in the Emergency Department: A Systematic Review and Meta-Analysis.急诊科老年患者谵妄的危险因素:系统评价和荟萃分析。
Ann Emerg Med. 2021 Oct;78(4):549-565. doi: 10.1016/j.annemergmed.2021.03.005. Epub 2021 Jun 12.
3
Reduced exposure to vasopressors through permissive hypotension to reduce mortality in critically ill people aged 65 and over: the 65 RCT.
通过允许性低血压减少血管加压药的使用以降低 65 岁及以上危重症患者死亡率的 65 RCT 研究
Health Technol Assess. 2021 Feb;25(14):1-90. doi: 10.3310/hta25140.
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Current Controversies in Caring for the Critically Ill Pulmonary Embolism Patient.重症肺栓塞患者护理中的当前争议
Emerg Med Clin North Am. 2020 Nov;38(4):931-944. doi: 10.1016/j.emc.2020.06.012. Epub 2020 Aug 12.
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Controlled hypotension versus normotensive resuscitation strategy for people with ruptured abdominal aortic aneurysm.腹主动脉瘤破裂患者的控制性低血压与正常血压复苏策略对比
Cochrane Database Syst Rev. 2018 Jun 13;6(6):CD011664. doi: 10.1002/14651858.CD011664.pub3.
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Pooled analysis of higher versus lower blood pressure targets for vasopressor therapy septic and vasodilatory shock.升压治疗脓毒性和血管扩张性休克时较高与较低血压目标值的汇总分析。
Intensive Care Med. 2018 Jan;44(1):12-21. doi: 10.1007/s00134-017-5016-5. Epub 2017 Dec 19.
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CARE guidelines for case reports: explanation and elaboration document.病例报告的CARE指南:解释与阐述文件。
J Clin Epidemiol. 2017 Sep;89:218-235. doi: 10.1016/j.jclinepi.2017.04.026. Epub 2017 May 18.
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