Chablé-Vega Manuel A, García-Hernández Eleazar, Martínez-Heredia Jorge E, Villalpando-Aguilar José L, Arreola-Enríquez Jesús, López-Rosas Itzel, Alatorre-Cobos Fulgencio
Colegio de Postgraduados Campus Campeche, Campeche, México.
Technological Institute of China, National Technological Institute of Mexico, Chiná, México.
Biotech Histochem. 2024 Jul;99(5):269-277. doi: 10.1080/10520295.2024.2367535. Epub 2024 Jun 13.
In recent years, a worldwide reassessment of natural dyes has occurred, driven by the health and environmental issues associated with synthetic dyes. L. is a tropical tree from which wood extracts were widely used in the textile industry during the 16 century. The logwood tree extract serves as a contemporary source of hematoxylin, a key dye in the globally prevalent hematoxylin-eosin staining method, a cornerstone in histopathological procedures. This paper will initially explore the re-emergence of natural dyes. Subsequently, it will focus on the historical, conventional, and innovative applications of logwood in the fields of medicine, histopathology, and nanotechnology, along with the status and alternative uses of the hematoxylin-eosin stain. Lastly, this paper will examine the current state of conservation and utilization of in Campeche, Mexico, a leading global producer of hematoxylin.