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具有可解释性的机器学习模型在肺癌风险预测中的疗效。

The efficacy of machine learning models in lung cancer risk prediction with explainability.

作者信息

Pathan Refat Khan, Shorna Israt Jahan, Hossain Md Sayem, Khandaker Mayeen Uddin, Almohammed Huda I, Hamd Zuhal Y

机构信息

Department of Computing and Information Systems, School of Engineering and Technology, Sunway University, Selangor, Malaysia.

Shamsun Nahar Khan Nursing College, Chattogram, Bangladesh.

出版信息

PLoS One. 2024 Jun 13;19(6):e0305035. doi: 10.1371/journal.pone.0305035. eCollection 2024.

Abstract

Among many types of cancers, to date, lung cancer remains one of the deadliest cancers around the world. Many researchers, scientists, doctors, and people from other fields continuously contribute to this subject regarding early prediction and diagnosis. One of the significant problems in prediction is the black-box nature of machine learning models. Though the detection rate is comparatively satisfactory, people have yet to learn how a model came to that decision, causing trust issues among patients and healthcare workers. This work uses multiple machine learning models on a numerical dataset of lung cancer-relevant parameters and compares performance and accuracy. After comparison, each model has been explained using different methods. The main contribution of this research is to give logical explanations of why the model reached a particular decision to achieve trust. This research has also been compared with a previous study that worked with a similar dataset and took expert opinions regarding their proposed model. We also showed that our research achieved better results than their proposed model and specialist opinion using hyperparameter tuning, having an improved accuracy of almost 100% in all four models.

摘要

在众多癌症类型中,截至目前,肺癌仍是全球最致命的癌症之一。许多研究人员、科学家、医生以及其他领域的人士持续为早期预测和诊断这一课题做出贡献。预测中的一个重大问题是机器学习模型的黑箱性质。尽管检测率相对令人满意,但人们仍不清楚模型是如何做出该决策的,这在患者和医护人员中引发了信任问题。这项工作在与肺癌相关参数的数值数据集上使用了多种机器学习模型,并比较了性能和准确性。比较之后,使用不同方法对每个模型进行了解释。本研究的主要贡献在于对模型为何做出特定决策给出逻辑解释,以赢得信任。本研究还与之前一项使用类似数据集并就其提出的模型征求专家意见的研究进行了比较。我们还表明,通过超参数调整,我们的研究比他们提出的模型和专家意见取得了更好的结果,在所有四个模型中准确率提高了近100%。

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