Gottlieb G L, Myklebust B M, Stefoski D, Groth K, Kroin J, Penn R D
Neurology. 1985 May;35(5):699-704. doi: 10.1212/wnl.35.5.699.
Electrical stimulation of the spinal cord (SCS) to reduce spasticity was evaluated in seven patients who, along with their physicians, perceived significant and prompt benefit from stimulation. In two 24-hour test periods, on or off stimulation, we used two independent methods of evaluation: quantitative measures of joint compliance and stretch reflexes, and a standardized neurologic examination. Neither method did better than chance in determining whether SCS was actually being received. Problems with the experimental protocol are discussed, but the results cannot be interpreted as supporting the efficacy of SCS as a treatment for spasticity.
对七名患者进行了脊髓电刺激（SCS）以减轻痉挛的评估，这些患者及其医生都认为刺激带来了显著且迅速的益处。在两个24小时的测试期内，分别处于刺激开启或关闭状态，我们使用了两种独立的评估方法：关节顺应性和牵张反射的定量测量，以及标准化的神经学检查。在确定是否实际接受了SCS方面，这两种方法都不比随机猜测更有效。文中讨论了实验方案存在的问题，但这些结果不能被解释为支持SCS作为治疗痉挛的有效性。
