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绿色合成的银纳米粒子在烧伤治疗中的应用:综述。

Application of green synthesized silver nanoparticles in Burn therapy: a review.

机构信息

Department of Pharmaceutics, College of Pharmacy, Najran University, Najran.

Department of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia.

出版信息

Pharmazie. 2024 May 15;79(3):42-48. doi: 10.1691/ph.2024.3045.

Abstract

Silver nanoparticles (AgNPs), owing to their unusual characteristics, have been used in various pharmaceutical, cosmetic, and healthcare products. AgNPs, with their exceptional biological potential, exhibit antibacterial, antifungal, antiviral, anti-inflammatory, anticancer, and wound healing properties and have been extensively used in burn therapy. Several studies have established the use of silver nanoparticles in the treatment of burn injuries, resulting in reduced inflammation, quick tissue regeneration, and the remarkable creation of collagen fibers. Conventional physical and chemical techniques have synthesized AgNPs, but they appear to be highly costly and hazardous. Recently, there has been considerable interest in the synthesis of AgNPs using the green chemistry approach because of its tremendous benefits, including being non-toxic, low energy consumption, pollution-free, economical, environmentally friendly, and more sustainable. This review emphasizes the green synthesis of AgNPs using bacteria, fungi, plants, and other microorganisms and the current research related to the application of green synthesized AgNPs in burn therapy, including the biological aspects of AgNPs, their mode of action, and any possible detrimental effects.

摘要

银纳米粒子(AgNPs)由于其独特的特性,已被广泛应用于各种药物、化妆品和医疗保健产品中。AgNPs 具有非凡的生物学潜力,表现出抗菌、抗真菌、抗病毒、抗炎、抗癌和伤口愈合的特性,并已被广泛应用于烧伤治疗。多项研究已经证实了银纳米粒子在烧伤治疗中的应用,可减轻炎症、快速组织再生,并显著生成胶原蛋白纤维。传统的物理和化学技术已经合成了 AgNPs,但它们似乎成本高昂且具有潜在危害。最近,由于其巨大的益处,包括无毒、低能耗、无污染、经济、环保和更可持续性,使用绿色化学方法合成 AgNPs 引起了广泛关注。本综述强调了使用细菌、真菌、植物和其他微生物进行 AgNPs 的绿色合成,以及当前关于绿色合成的 AgNPs 在烧伤治疗中的应用的研究,包括 AgNPs 的生物学方面、作用模式以及任何可能的有害影响。

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