Liku Nzisa, Mburu Caroline, Lafond Kathryn E, Ebama Malembe, Athman Mamu, Swaleh Salma, Jewa Isaac, Ngware Elen, Njenga Virginia, Kiptoo Elizabeth, Munyao Catherine, Miano Christine, Anyango Edwina, Thuo Samson, Matini Wycliffe, Mirieri Harriet, Otieno Nancy, Athman Mwanasha, Chanzera Patrick, Awadh Zahra, Muthoni Monica, Kingori Patrick, Kariuki Njenga M, Emukule Gideon O, Osoro Eric, Tabu Collins, Dawa Jeanette
Influenza Program, U.S. Centers for Disease Control and Prevention, Nairobi, Kenya.
Department of Social Anthropology, University of St Andrews, Scotland, UK.
Vaccine X. 2024 May 27;19:100507. doi: 10.1016/j.jvacx.2024.100507. eCollection 2024 Aug.
Influenza is a significant contributor to acute respiratory infections (ARI), and children < 5 years are at increased risk of severe influenza disease. In Kenya the influenza vaccine is not included in the Kenya Expanded Programme on Immunization (KEPI). To inform roll-out of a national influenza vaccination program, we implemented an influenza vaccine demonstration project in Nakuru and Mombasa counties in Kenya from 2019 to 2021 and set out to establish factors driving influenza vaccine acceptance and hesitancy among caregivers of children aged 6-23 months.
Using semi-structured questionnaires, we conducted eight focus group discussions among community members and twelve key informant interviews among healthcare workers to elicit both lay and expert opinions. Thematic analysis of the interviews was conducted using the World Health Organization's "3 Cs" model of vaccine hesitancy to determine reasons for acceptance or hesitancy of the influenza vaccine.
The influenza vaccine was well received among community members and healthcare workers though concerns were raised. Vaccine hesitancy was fuelled by misconceptions about reasons for introducing the vaccine (confidence), perceptions that influenza was not a serious disease (complacency) and administrative fees required at some facilities (convenience). Despite the use of various advocacy, communication and social mobilisation strategies targeted at educating the community on the influenza disease and importance of vaccination, there remained a perception of inadequate reach of the sensitization among some community members. Contextual factors such as the COVID-19 pandemic affected uptake, and parents expressed concern over the growing number of vaccines recommended for children.
Despite lingering concerns, caregivers had their children vaccinated indicating that vaccine hesitancy exists, even among those who accepted the vaccine for their children. Efforts targeted at increasing confidence in and reducing misconceptions towards vaccines through effective communication strategies, are likely to lead to increased vaccine uptake.
流感是急性呼吸道感染(ARI)的一个重要促成因素,5岁以下儿童患重症流感疾病的风险更高。在肯尼亚,流感疫苗未被纳入肯尼亚扩大免疫规划(KEPI)。为了为全国流感疫苗接种计划的推出提供信息,我们于2019年至2021年在肯尼亚的纳库鲁县和蒙巴萨县实施了一项流感疫苗示范项目,并着手确定推动6至23个月大儿童的看护人接受和犹豫接种流感疫苗的因素。
我们使用半结构化问卷,在社区成员中进行了8次焦点小组讨论,并在医护人员中进行了12次关键信息人访谈,以收集外行和专家的意见。使用世界卫生组织的疫苗犹豫“3C”模型对访谈进行主题分析,以确定接受或犹豫接种流感疫苗的原因。
尽管存在一些担忧,但社区成员和医护人员对流感疫苗的接受度良好。对引入疫苗的原因存在误解(信心)、认为流感不是严重疾病(自满)以及一些机构收取行政费用(便利)等因素加剧了疫苗犹豫。尽管采取了各种宣传、沟通和社会动员策略来教育社区了解流感疾病和疫苗接种的重要性,但一些社区成员仍然认为宣传的覆盖面不足。诸如COVID-19大流行等背景因素影响了疫苗接种率,家长们对推荐给儿童的疫苗数量不断增加表示担忧。
尽管担忧仍然存在,但看护人还是让他们的孩子接种了疫苗,这表明即使在那些为孩子接受疫苗接种的人中也存在疫苗犹豫。通过有效的沟通策略来增强对疫苗的信心并减少误解的努力,可能会提高疫苗接种率。