Department of Chemistry, School of Chemistry and Chemical Engineering, Key Laboratory of Surface & Interface Science of Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, 310018, China.
Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Hangzhou First People's Hospital, Hangzhou, 310006, China.
Chembiochem. 2024 Nov 4;25(21):e202400320. doi: 10.1002/cbic.202400320. Epub 2024 Aug 2.
Vertically-ordered mesoporous silica films (VMSF, also named as silica isoporous membranes) have shown tremendous potential in the field of electroanalytical sensors due to their unique features in terms of controllable and ultrasmall nanopores, high molecular selectivity and permeability, and mechanical stability. This review will present the recent progress on the biomedical analytical applications of VMSF, focusing on the small biomolecules, diseases-related biomarkers, drugs and cancer cells. Finally, conclusions with recent developments and future perspective of VMSF in the relevant fields will be envisioned.
有序介孔硅薄膜（VMSF，也称为硅质等孔膜）具有可控的超小孔径、高分子选择性和渗透性以及机械稳定性等独特特性，在电分析传感器领域显示出巨大的潜力。本综述将介绍 VMSF 在生物医学分析应用方面的最新进展，重点介绍小分子、与疾病相关的生物标志物、药物和癌细胞。最后，将对 VMSF 在相关领域的最新发展和未来展望进行展望。
