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双冲洗还是单冲洗?根管螯合剂对根管封闭剂的渗透作用。

Dual- or single rinse? The tubular sealer penetration of endodontic chelating agents.

机构信息

Department of Endodontics, Yeditepe University Faculty of Dentistry, Yeditepe University, Istanbul, Turkey.

Department of Genetics and Bioengineering, Faculty of Engineering, Yeditepe University, Istanbul, Turkey.

出版信息

PLoS One. 2024 Jun 14;19(6):e0303377. doi: 10.1371/journal.pone.0303377. eCollection 2024.

Abstract

INTRODUCTION

In this study, we aimed to compare the effectiveness of various chelating agents, ethilenediaminetetraacetic acid (EDTA), citric acid (CA), and etidronic acid (HEDP) mixed in two different forms, in removing the smear layer and promoting the penetration of an endodontic sealer into the dentinal tubules of extracted single-rooted teeth.

METHODS

The study used 75 teeth divided into five groups: 17% EDTA, 10% CA, 9% HEDP + NaOCl, 9% HEDP + distilled water (DW), and a control (DW) group. Scanning electron microscopy was used to assess smear layer removal and confocal laser microscopy was used to evaluate tubular sealer penetration at different depths from the apical tip.

RESULTS

Sealer penetration was highest with 17% EDTA and 10% CA as compared with the other agents (p<0.001). At the cervical third, the sealer penetration for EDTA, HEDP + NaOCl, and HEDP + DW groups were significantly different than those in DW (p = 0.020). For the middle third, EDTA, CA, and HEDP + NaOCl groups were significantly higher than those of the DW group (p<0.001). Cervical-level values were significantly higher than apical-level values for HEDP + NaOCl, HEDP + DW, and DW (p<0.001). Smear layer removal was lower with 9% HEDP + DW than with 17% EDTA and 10% CA at all depths (p<0.001). A significancy in smear layer removal was observed between 10% CA and control (p = 0.015) in middle depth.

CONCLUSION

Within the limitations of this study, highest values were seen in EDTA and CA in terms of sealer penetration and smear layer removal. In the light of these findings, the use of strong chelating agents highlights better clinical efficiency than dual-rinse or single HEDP irrigation.

摘要

简介

本研究旨在比较乙二胺四乙酸(EDTA)、柠檬酸(CA)和羟基亚乙基二膦酸(HEDP)三种螯合剂以两种不同形式混合时,清除玷污层并促进根管封闭剂渗透进入离体单根牙牙本质小管的效果。

方法

本研究共使用 75 颗牙,分为 5 组:17% EDTA、10% CA、9% HEDP+次氯酸钠、9% HEDP+蒸馏水(DW)和空白对照组(DW)。使用扫描电子显微镜评估玷污层的清除效果,使用共聚焦激光显微镜评估根管封闭剂在根尖顶点不同深度的渗透情况。

结果

与其他试剂相比,17% EDTA 和 10% CA 时的封闭剂渗透效果最高(p<0.001)。在颈三分之一处,EDTA、HEDP+次氯酸钠和 HEDP+DW 组的封闭剂渗透深度明显大于 DW 组(p=0.020)。在中三分之一处,EDTA、CA 和 HEDP+次氯酸钠组的封闭剂渗透深度明显大于 DW 组(p<0.001)。在颈三分之一处,HEDP+次氯酸钠、HEDP+DW 和 DW 组的封闭剂渗透深度明显大于根尖三分之一处(p<0.001)。在所有深度处,9% HEDP+DW 的玷污层清除效果均低于 17% EDTA 和 10% CA(p<0.001)。在中间深度处,10% CA 与空白对照组之间的玷污层清除效果有显著性差异(p=0.015)。

结论

在本研究的限制条件下,EDTA 和 CA 时封闭剂渗透和玷污层清除效果最好。鉴于这些发现,使用强力螯合剂比双冲洗或单 HEDP 冲洗具有更好的临床效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/23c2/11178202/9792864743cc/pone.0303377.g001.jpg

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