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棘突间固定减压治疗腰椎滑脱症与后路腰椎椎体间融合术的疗效和安全性比较:一项初步研究。

The efficacy and safety of decompression with interspinous fixation for lumbar spondylolisthesis when compared with posterior lumbar interbody fusion: A pilot study.

机构信息

Department of Neurosurgery, Chonnam National University Hospital & Medical School, Gwangju, Republic of Korea.

Department of Rheumatology, Chonnam National University Hospital & Medical School, Gwangju, Republic of Korea.

出版信息

Medicine (Baltimore). 2024 Jun 14;103(24):e38501. doi: 10.1097/MD.0000000000038501.

DOI:10.1097/MD.0000000000038501
PMID:38875412
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11175900/
Abstract

Posterior lumbar interbody fusion (PLIF) is widely used to treat degenerative spondylolisthesis because it provides definitive decompression and fixation. Although it has several advantages, it has some disadvantages and risks, such as paraspinal muscle injury, potential intraoperative bleeding, postoperative pain, hardware failure, subsidence, and medical comorbidity. Lumbar decompressive bilateral laminectomy with interspinous fixation (DLISF) is less invasive and can be used on some patients with PLIF, but this has not been reported. To compare the efficacy and safety of DLISF in the treatment of low-grade lumbar spondylolisthesis with that of PLIF. We retrospectively analyzed the medical records of 81 patients with grade I spondylolisthesis, who had undergone PLIF or DLISF and were followed up for more than 1 year. Surgical outcomes, visual analog scale, radiologic outcomes, including Cobb angle and difference in body translation, and postoperative complications were assessed. Forty-one patients underwent PLIF, whereas 40 underwent DLISF. The operative times were 271.0 ± 57.2 and 150.6 ± 29.3 minutes for the PLIF and DLISF groups, respectively. The estimated blood loss was significantly higher in the PLIF group versus the DLISF group (290.7 ± 232.6 vs 122.2 ± 82.7 mL, P < .001). Body translation did not differ significantly between the 2 groups. Overall pain improved during the 1-year follow-up when compared with baseline data. Medical complications were significantly lower in the DLISF group, whereas perioperative complications and hardware issues were higher in the PLIF group. The outcomes of DLISF, which is less invasive, were comparable to PLIF outcomes in patients with low-grade spondylolisthesis. As a salvage technique, DLISF may be a good option when compared with PLIF.

摘要

后路腰椎体间融合术(PLIF)广泛应用于治疗退行性脊椎滑脱,因为它可以提供明确的减压和固定。尽管它有几个优点,但也有一些缺点和风险,如椎旁肌损伤、潜在的术中出血、术后疼痛、内固定失败、下沉和合并症。腰椎减压双侧椎板切除术伴棘突间固定术(DLISF)创伤较小,可用于一些需要 PLIF 的患者,但尚未有报道。比较 DLISF 治疗低等级腰椎滑脱的疗效和安全性与 PLIF 的疗效和安全性。我们回顾性分析了 81 例 I 度脊椎滑脱患者的病历,这些患者接受了 PLIF 或 DLISF 治疗,并随访了 1 年以上。评估手术结果、视觉模拟量表、影像学结果,包括 Cobb 角和身体平移差异,以及术后并发症。41 例患者行 PLIF,40 例行 DLISF。PLIF 和 DLISF 组的手术时间分别为 271.0±57.2 和 150.6±29.3 分钟。PLIF 组的估计失血量明显高于 DLISF 组(290.7±232.6 比 122.2±82.7ml,P<0.001)。两组间身体平移差异无统计学意义。与基线数据相比,在 1 年随访期间,整体疼痛均有改善。DLISF 组的医疗并发症明显低于 PLIF 组,而 PLIF 组的围手术期并发症和内固定问题较高。在低等级脊椎滑脱患者中,作为一种挽救技术,DLISF 的疗效与 PLIF 相当。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8e6/11175900/601bcba41c39/medi-103-e38501-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8e6/11175900/01915c307708/medi-103-e38501-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8e6/11175900/df7d3c7eeb2f/medi-103-e38501-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8e6/11175900/601bcba41c39/medi-103-e38501-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8e6/11175900/01915c307708/medi-103-e38501-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8e6/11175900/df7d3c7eeb2f/medi-103-e38501-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8e6/11175900/601bcba41c39/medi-103-e38501-g003.jpg

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