Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 54124, Greece.
Department of Biopathology, Hippokratio General Hospital, Thessaloniki 54642, Greece.
Med Mycol. 2024 Jul 4;62(7). doi: 10.1093/mmy/myae062.
Candida auris is an emerging fungal pathogen associated with multi-drug resistance rates and widespread outbreaks in hospitals and healthcare units worldwide. Sequencing studies have revealed that different clonal lineages of the fungus seem to be prevalent among distinct geographical sites. The first case of C. auris in Northern Greece was reported in Thessaloniki in October 2022, almost 2 years after the first isolation in Greece (Athens 2019). The Mycology Laboratory of the Medical School of Aristotle University of Thessaloniki stands as the reference laboratory for fungal diseases in Northern Greece and a meticulous search for the yeast, in plenty of suspicious samples, has been run since 2019 in the Lab as well as a retrospective analysis of all its yeasts' collection, back to 2008, with negative results for the presence of C. auris. Here, are presented the findings concerning the outbreak and surveillance of C. auris in Northern Greece, mainly the region of Thessaloniki and the broader area of Macedonia, from October 2022 until August 2023. The isolates from Northern Greece continue to fall in Clade I and present with an almost equal and stable sensitivity profile until now.
耳念珠菌是一种新兴的真菌病原体，与全球医院和医疗机构中的多药耐药率和广泛爆发有关。测序研究表明，该真菌的不同克隆谱系似乎在不同地理区域流行。希腊北部首例耳念珠菌病例于 2022 年 10 月在塞萨洛尼基报告，这是该真菌在希腊首次分离（2019 年，雅典）后近 2 年。亚里士多德大学萨洛尼卡医学院的真菌学实验室是希腊北部真菌病的参考实验室，自 2019 年以来，该实验室一直在大量可疑样本中仔细寻找酵母菌，并对其所有酵母菌的收集进行回顾性分析，追溯到 2008 年，结果均为阴性，未发现耳念珠菌。本文介绍了 2022 年 10 月至 2023 年 8 月期间，希腊北部（主要是塞萨洛尼基地区和马其顿大区）耳念珠菌的爆发和监测情况。来自希腊北部的分离株继续属于 I 型分支，迄今为止，其药敏谱几乎保持一致且稳定。
