Thaysen J H, Thomsen H S, Sass A, Kristensen J K
Acta Med Scand. 1985;217(2):197-204. doi: 10.1111/j.0954-6820.1985.tb01656.x.
Renal volume was determined by repeated CT scanning in 26 patients with adult polycystic kidney disease after institution of replacement therapy for terminal renal failure. Thirteen patients, treated for an average period of 6.7 years (SD 3.4, range 1.1-13.7), had a functioning necrokidney graft at the close of the study and had been grafted for 80.8% (SD 18) of the total treatment time. They showed a reduction of renal volume averaging 1.07% (SD 0.89) per month. Thirteen patients, treated for an average period of 5.7 years (SD 3.3, range 1.2-12.2), were on dialysis at the close of the study. Four had been on dialysis only, 9 had carried one or more (rejected) necrokidney grafts for 22.8% (SD 25) of the total treatment time. Three of them showed a significant increase in renal volume, whereas ten showed a decrease. The average change of renal volume in the entire group was -0.28% (SD 1.36) per month, significantly smaller than in the transplanted patients (p less than 0.01). It is concluded that polycystic kidneys shrink after successful grafting, whereas volume changes vary on dialysis treatment.
在26例终末期肾衰竭接受替代治疗的成年多囊肾病患者中，通过重复CT扫描测定肾脏体积。13例患者平均治疗6.7年（标准差3.4，范围1.1 - 13.7年），在研究结束时移植肾有功能，移植时间占总治疗时间的80.8%（标准差18）。他们的肾脏体积每月平均减少1.07%（标准差0.89）。13例患者平均治疗5.7年（标准差3.3，范围1.2 - 12.2年），在研究结束时接受透析治疗。4例仅接受透析治疗，9例曾接受一个或多个（已排斥）移植肾，移植时间占总治疗时间的22.8%（标准差25）。其中3例肾脏体积显著增加，而10例减少。整个组的肾脏体积平均每月变化为 - 0.28%（标准差1.36），显著小于移植患者（p < 0.01）。结论是成功移植后多囊肾会缩小，而透析治疗时体积变化各不相同。
