Bernard G R, Brigham K L
Annu Rev Med. 1985;36:195-205. doi: 10.1146/annurev.me.36.020185.001211.
The Adult Respiratory Distress Syndrome is a complication of many illnesses such as sepsis, pneumonia and trauma afflicting over 150,000 patients per year. While progress in intensive care medicine has increased the survival rates in many of these underlying illnesses, major obstacles remain in the successful therapy of ARDS. Animal and human investigations shed light on the pathophysiology of the illness that is allowing researchers to formulate promising new treatment strategies.
成人呼吸窘迫综合征是败血症、肺炎和创伤等多种疾病的并发症,每年影响超过15万名患者。虽然重症监护医学的进展提高了许多这些基础疾病的存活率,但在成人呼吸窘迫综合征的成功治疗方面仍存在重大障碍。动物和人体研究揭示了该疾病的病理生理学,这使研究人员能够制定出有前景的新治疗策略。