Elmorsy Ekramy, Alshammari Dhaidan M, Alanazi Madhawi A, Alshammari Khulud Hamed S, Alanazi Reem S, Alanazi Reem Mohammed Z, Alruwaili Shmoukh Mushref, Alanazi Ghadah Khalid H
Pathology, Northern Border University, Arar, SAU.
Otorhinolaryngology, Ministry of Health, Arar, SAU.
Cureus. 2024 May 16;16(5):e60429. doi: 10.7759/cureus.60429. eCollection 2024 May.
The purpose of this study was to assess the awareness of ototoxicity among medical doctors in Arar City, Saudi Arabia.
This is a cross-sectional study based on a pre-formed validated questionnaire (Appendix) that included three sections covering participants' demographic data (three questions), their attitudes (five questions), and knowledge (13 questions) regarding drug-induced ototoxicity.
After obtaining their informed consent, 213 physicians from government and private sector health facilities in Arar were enrolled in the study. Interns and general practitioners represented 57.8% of the participants; consultants represented 17.8%. Only 71.8% of participants were interested in drug-induced ototoxicity, while 26.3% considered ototoxicity a rare complication. Approximately 90% of the participants were knowledgeable about the adverse effects of drugs on the vestibulocochlear system, and 26.7% reported having experienced cases of drug-induced ototoxicity in their practice. Participants showed an overall knowledge score about ototoxicity of 9.3±3.27 (out of 14). The knowledge score was significantly higher (p-value=0.0007) for participants with more years of clinical experience. The most widely known ototoxic drug for participants was frusemide (72.3%), followed by aminoglycoside (68.5%), while acetaminophen (44.1%) ototoxicity was the least known among participants.
Awareness of drug-induced ototoxicity is satisfactory among physicians in the Northern Borders region. However, workshops about all types of drugs with ototoxic effects and the main lines for the management of drug-induced ototoxicity are recommended to increase awareness.
本研究旨在评估沙特阿拉伯阿拉尔市医生对耳毒性的认知情况。
这是一项横断面研究,基于一份预先设计并经验证的问卷(附录),该问卷包括三个部分,涵盖参与者的人口统计学数据(三个问题)、他们对药物性耳毒性的态度(五个问题)以及知识(13个问题)。
在获得他们的知情同意后,来自阿拉尔市政府和私立医疗机构的213名医生参与了该研究。实习生和全科医生占参与者的57.8%;顾问占17.8%。只有71.8%的参与者对药物性耳毒性感兴趣,而26.3%的人认为耳毒性是一种罕见的并发症。大约90%的参与者了解药物对前庭蜗神经的不良影响,26.7%的人报告在他们的临床实践中遇到过药物性耳毒性病例。参与者耳毒性的总体知识得分为9.3±3.27(满分14分)。临床经验更丰富的参与者的知识得分显著更高(p值=0.0007)。参与者最熟知的耳毒性药物是速尿(72.3%),其次是氨基糖苷类(68.5%),而对乙酰氨基酚的耳毒性(44.1%)在参与者中知晓度最低。
北部边境地区医生对药物性耳毒性的认知情况令人满意。然而,建议举办关于所有具有耳毒性作用的药物类型以及药物性耳毒性管理主要方法的研讨会,以提高认知度。