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沙特阿拉伯阿拉尔市医生对耳毒性药物的认知与态度

Awareness and Attitude About Ototoxic Drugs Among Medical Doctors in Arar City, Saudi Arabia.

作者信息

Elmorsy Ekramy, Alshammari Dhaidan M, Alanazi Madhawi A, Alshammari Khulud Hamed S, Alanazi Reem S, Alanazi Reem Mohammed Z, Alruwaili Shmoukh Mushref, Alanazi Ghadah Khalid H

机构信息

Pathology, Northern Border University, Arar, SAU.

Otorhinolaryngology, Ministry of Health, Arar, SAU.

出版信息

Cureus. 2024 May 16;16(5):e60429. doi: 10.7759/cureus.60429. eCollection 2024 May.

Abstract

OBJECTIVES

The purpose of this study was to assess the awareness of ototoxicity among medical doctors in Arar City, Saudi Arabia.

METHODS

This is a cross-sectional study based on a pre-formed validated questionnaire (Appendix) that included three sections covering participants' demographic data (three questions), their attitudes (five questions), and knowledge (13 questions) regarding drug-induced ototoxicity.

RESULTS

After obtaining their informed consent, 213 physicians from government and private sector health facilities in Arar were enrolled in the study. Interns and general practitioners represented 57.8% of the participants; consultants represented 17.8%. Only 71.8% of participants were interested in drug-induced ototoxicity, while 26.3% considered ototoxicity a rare complication. Approximately 90% of the participants were knowledgeable about the adverse effects of drugs on the vestibulocochlear system, and 26.7% reported having experienced cases of drug-induced ototoxicity in their practice. Participants showed an overall knowledge score about ototoxicity of 9.3±3.27 (out of 14). The knowledge score was significantly higher (p-value=0.0007) for participants with more years of clinical experience. The most widely known ototoxic drug for participants was frusemide (72.3%), followed by aminoglycoside (68.5%), while acetaminophen (44.1%) ototoxicity was the least known among participants.

CONCLUSION

Awareness of drug-induced ototoxicity is satisfactory among physicians in the Northern Borders region. However, workshops about all types of drugs with ototoxic effects and the main lines for the management of drug-induced ototoxicity are recommended to increase awareness.

摘要

目的

本研究旨在评估沙特阿拉伯阿拉尔市医生对耳毒性的认知情况。

方法

这是一项横断面研究,基于一份预先设计并经验证的问卷(附录),该问卷包括三个部分,涵盖参与者的人口统计学数据(三个问题)、他们对药物性耳毒性的态度(五个问题)以及知识(13个问题)。

结果

在获得他们的知情同意后,来自阿拉尔市政府和私立医疗机构的213名医生参与了该研究。实习生和全科医生占参与者的57.8%;顾问占17.8%。只有71.8%的参与者对药物性耳毒性感兴趣,而26.3%的人认为耳毒性是一种罕见的并发症。大约90%的参与者了解药物对前庭蜗神经的不良影响,26.7%的人报告在他们的临床实践中遇到过药物性耳毒性病例。参与者耳毒性的总体知识得分为9.3±3.27(满分14分)。临床经验更丰富的参与者的知识得分显著更高(p值=0.0007)。参与者最熟知的耳毒性药物是速尿(72.3%),其次是氨基糖苷类(68.5%),而对乙酰氨基酚的耳毒性(44.1%)在参与者中知晓度最低。

结论

北部边境地区医生对药物性耳毒性的认知情况令人满意。然而,建议举办关于所有具有耳毒性作用的药物类型以及药物性耳毒性管理主要方法的研讨会,以提高认知度。

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本文引用的文献

1
Otologic safety of intratympanic N-acetylcysteine in an animal model.
Int J Pediatr Otorhinolaryngol. 2023 Oct;173:111702. doi: 10.1016/j.ijporl.2023.111702. Epub 2023 Aug 23.
2
Hearing Loss and Dementia Prevalence in Older Adults in the US.
JAMA. 2023 Jan 10;329(2):171-173. doi: 10.1001/jama.2022.20954.
3
Prevalence of Polypharmacy in Patients With Vestibular and Balance Complaints.
Ear Hear. 2023;44(3):506-517. doi: 10.1097/AUD.0000000000001292. Epub 2022 Nov 15.
4
Genetic Causes of Hearing Loss in a Large Cohort of Cochlear Implant Recipients.
Otolaryngol Head Neck Surg. 2022 Apr;166(4):734-737. doi: 10.1177/01945998211021308. Epub 2021 Jun 22.
5
Addressing the global burden of hearing loss.
Lancet. 2021 Mar 13;397(10278):945-947. doi: 10.1016/S0140-6736(21)00522-5.
6
Drugs inducing hearing loss, tinnitus, dizziness and vertigo: an updated guide.
Eur Rev Med Pharmacol Sci. 2020 Aug;24(15):7946-7952. doi: 10.26355/eurrev_202008_22477.
7
Liver radiologic findings of chemotherapy-induced toxicity in liver colorectal metastases patients.
Eur Rev Med Pharmacol Sci. 2019 Nov;23(22):9697-9706. doi: 10.26355/eurrev_201911_19531.
8
Mitochondrial DNA mutations associated with aminoglycoside induced ototoxicity.
J Otol. 2017 Mar;12(1):1-8. doi: 10.1016/j.joto.2017.02.001. Epub 2017 Feb 11.
9
Ototoxic effects and mechanisms of loop diuretics.
J Otol. 2016 Dec;11(4):145-156. doi: 10.1016/j.joto.2016.10.001. Epub 2016 Oct 27.
10
Anti-cancer characteristics and ototoxicity of platinum(II) amine complexes with only one leaving ligand.
PLoS One. 2018 Mar 7;13(3):e0192505. doi: 10.1371/journal.pone.0192505. eCollection 2018.

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