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揭示大流行期间孟加拉国不同人群中 COVID-19 的发生情况。

Unveiling the occurrence of COVID-19 in a diverse Bangladeshi population during the pandemic.

机构信息

Department of Biochemistry and Molecular Biology, Laboratory of Neuroscience and Neurogenetics, University of Dhaka, Dhaka, Bangladesh.

Dr. Farida Haq Memorial Ibrahim General Hospital, COVID-19 Diagnostic Laboratory, Gazipur, Bangladesh.

出版信息

Front Public Health. 2024 May 31;12:1363971. doi: 10.3389/fpubh.2024.1363971. eCollection 2024.

Abstract

INTRODUCTION

COVID-19 pandemic hit Bangladesh with relatively low intensity, unlike its neighbors India and European countries and USA.

METHODS

The present report included data of 8,480 individuals tested for COVID-19 RT-PCR of the workers and officials from readymade garments (RMG) industry in Chandra area in Gazipur. The present data looked into the clinic-demographic factors associated with the susceptibility of the condition.

RESULT

The data elucidated the susceptibility of the individuals to SARS-CoV-2 based on age, gender, pre-existing health conditions, and the presence of symptoms. It was observed that individuals aged over 60 had the highest rate of COVID-19 positivity, and men exhibited a higher infection rate compared to women. Regardless of age, fever and cough were the most frequently reported symptoms. Two-thirds of the individuals included in this report appeared to be asymptomatic carriers. The prevalence of comorbidities among individuals who tested positive for COVID-19 was notably higher, and this exhibited a gender-specific pattern.

DISCUSSION

Although our study provides important epidemiological insights into the initial year of the pandemic among Bangladeshi populations, it can also add value for future drug and vaccine development. However, it is essential to acknowledge the limitations like - restriction of public movement, unavailability of vehicle yielding a selection bias, due to the lockdown conditions imposed owing to the pandemic and the diverse characteristics of the participants. The report emphasizes the significance of figuring out how age, gender, and underlying health conditions impact susceptibility to and transmission of COVID-19, thereby providing valuable insights for public health strategies and future research initiatives.

摘要

简介

与印度、欧洲国家和美国等邻国相比,COVID-19 大流行在孟加拉国的强度相对较低。

方法

本报告包括来自加济布尔钱德拉地区成衣(RMG)行业工人和官员的 8480 名接受 COVID-19 RT-PCR 检测的人员的数据。本报告研究了与该病症易感性相关的临床人口统计学因素。

结果

根据年龄、性别、既往健康状况和症状存在情况,数据阐明了个体对 SARS-CoV-2 的易感性。结果表明,60 岁以上的个体 COVID-19 阳性率最高,男性感染率高于女性。无论年龄大小,发热和咳嗽是最常报告的症状。报告中纳入的三分之二的个体似乎是无症状携带者。COVID-19 检测呈阳性的个体中合并症的患病率明显更高,并且表现出性别特异性模式。

讨论

尽管我们的研究为孟加拉国人群大流行初始年份的流行病学提供了重要见解,但它也可以为未来的药物和疫苗开发增添价值。然而,必须认识到一些限制因素,例如:由于大流行期间实施的封锁条件,公众行动受限、缺乏车辆导致选择偏差,以及参与者的不同特征。该报告强调了确定年龄、性别和基础健康状况如何影响 COVID-19 的易感性和传播的重要性,从而为公共卫生策略和未来的研究计划提供了有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/719a/11176491/df743d5d3ce4/fpubh-12-1363971-g001.jpg

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